Findings

What do systematic reviews say?

577 questions · 585 findings · 57 reviews

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No studies found 61 · 10.4%GRADE not reported 46 · 7.9%Very low 206 · 35.2%Low 210 · 35.9%Moderate 52 · 8.9%High 10 · 1.7%

PEG vs no enteral tube feeding

Pressure ulcerse · people with severe dementia

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 4421 participants
Moderate

PEG vs no enteral tube feeding

Pain and comfort · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

PEG vs no enteral tube feeding

Improvement of nutritional status · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nasogastric tubes vs no enteral tube feeding

Survival time · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Nasogastric tubes vs no enteral tube feeding

Total mortalitya · people with severe dementia

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 236 participants
Very low

Nasogastric tubes vs no enteral tube feeding

Quality of life · people with severe dementia

The review found no eligible studies for this question.

1 finding from 1 review

Enteral tube feeding for people with severe dementia 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Growth · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 347 participants
Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Growth · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 55 participants
Low

Fish oil lipid emulsion (LE) vs another fish oil LE

PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – MOFS‐LE vs MFS‐LE · Parenterally fed preterm infants

Fish oil lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – MOFS‐LE vs MFS‐LE compared with another fish oil LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 0.96 [0.06, 14.65]
1 study · 55 participants
Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Death at hospital discharge · Parenterally fed preterm infants

Fish oil lipid emulsion (LE) showed no clear difference in death before discharge – MOFS‐LE vs MFS‐LE compared with another fish oil LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1 [0.15, 6.64]
1 study · 60 participants
Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Oxygen requirement at 36 weeks' postmenstrual age · Parenterally fed preterm infants

Fish oil lipid emulsion (LE) showed no clear difference in CLD (oxygen requirement at 36 weeks' postmenstrual age) – MOFS‐LE vs… compared with another fish oil LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1.16 [0.4, 3.35]
1 study · 55 participants
Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Any sepsis (clinical and/or culture positive) · Parenterally fed preterm infants

Fish oil lipid emulsion (LE) showed no clear difference in any sepsis (clinical or culture positive (or both)) – MOFS‐LE vs… compared with another fish oil LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1.69 [0.56, 5.11]
1 study · 55 participants
Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Conjugated bilirubin levels · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 55 participants
Low

Alternative lipid emulsion (LE) vs S‐LE

Growth rate – MS‐LE vs S‐LE · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Low

Alternative lipid emulsion (LE) vs S‐LE

PNALD/cholestasis (any definition) – OS‐LE vs S‐LE · Parenterally fed preterm infants

Alternative lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (any definition) – OS‐LE vs S‐LE compared with soybean oil‐based LE (S‐LE) (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1 [0.26, 3.86]
4 studies · 261 participants
Low

Alternative lipid emulsion (LE) vs S‐LE

PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – OS‐LE vs S‐LE · Parenterally fed preterm infants

Alternative lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – OS‐LE vs S‐LE compared with soybean oil‐based LE (S‐LE) (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1 [0.15, 6.82]
2 studies · 159 participants
Low

Fish oil lipid emulsion (LE) vs non‐fish oil LE

PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – all fish oil LE vs non‐fish oil LE (combined subgroups) · Parenterally fed preterm infants

Fish oil lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – all fish oil LE… compared with non‐fish oil LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 0.61 [0.24, 1.56]
4 studies · 328 participants
Low

Alternative lipid emulsion (LE) vs S‐LE

Death at hospital discharge · Parenterally fed preterm infants

Alternative lipid emulsion (LE) showed no clear difference in death before discharge – OS‐LE vs S‐LE compared with soybean oil‐based LE (S‐LE) (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1 [0.21, 4.82]
3 studies · 224 participants
Low

Alternative lipid emulsion (LE) vs S‐LE

Death of baby (up to discharge) · Parenterally fed preterm infants

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
GRADE not reported

Alternative lipid emulsion (LE) vs S‐LE

Any ROP – OS‐LE vs S‐LE · Parenterally fed preterm infants

It is very uncertain whether alternative lipid emulsion (LE) changes any ROP – OS‐LE vs S‐LE compared with soybean oil‐based LE (S‐LE) (very low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 0.98 [0.67, 1.43]
3 studies · 142 participants
Very low