Question · asked by 1 review

Fish oil lipid emulsion (LE) vs non‐fish oil LE: PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – all fish oil LE vs non‐fish oil LE (combined subgroups)

Fish oil lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – all fish oil LE… compared with non‐fish oil LE (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Fish oil lipid emulsion (LE) vs non‐fish oil LE
PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – all fish oil LE vs non‐fish oil LE (combined subgroups) · parenterally fed preterm infants
Fish oil lipid emulsion (LE) showed no clear difference in PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – all fish oil LE… compared with non‐fish oil LE (low certainty).
Lipid emulsions for parenterally fed preterm infants (2019) · Cochrane Headline outcomes only
RR 0.61 [0.24, 1.56]4 studies · 328 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Lipid emulsions for parenterally fed preterm infants
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.