Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

429 questions · 431 findings · 83 reviews

No studies found 89 · 20.6%GRADE not reported 34 · 7.9%Very low 93 · 21.6%Low 110 · 25.5%Moderate 79 · 18.3%High 26 · 6%

EGFR monoclonal antibody (cetuximab or nimotuzumab) plus standard therapy (radiotherapy or chemoradiotherapy) vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Participant satisfaction · People with squamous cell carcinoma of the oral cavity or oropharynx

The review found no eligible studies for this question.

1 finding from 1 review

EGFR monoclonal antibody (cetuximab or nimotuzumab) plus standard therapy (radiotherapy or chemoradiotherapy) vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Costs (direct and indirect) · People with squamous cell carcinoma of the oral cavity or oropharynx

The review found no eligible studies for this question.

1 finding from 1 review

Supervised exercise therapy following vascular intervention vs vascular intervention alone

All‐cause mortality · people with symptomatic peripheral arterial disease§

It is very uncertain whether supervised exercise therapy following vascular intervention changes mortality compared with vascular intervention alone (very low certainty).

1 finding from 1 review

Supervised exercise therapy following vascular intervention vs vascular intervention alone

Reintervention · people with symptomatic peripheral arterial disease§

It is very uncertain whether supervised exercise therapy following vascular intervention changes reintervention compared with vascular intervention alone (very low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death or stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher death or stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Long‐term ipsilateral stroke · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment probably leads to higher ipsilateral stroke compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Type of recurrent event · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment showed no clear difference in type of recurrent event compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Death · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment may leads to higher death compared with conventional medical treatment alone (low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs conventional medical treatment alone

Dependency · people with symptomatic intracranial artery stenosis

Endovascular therapy plus conventional medical treatment showed no clear difference in dependency compared with conventional medical treatment alone (moderate certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs medical treatment

Death or stroke · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in 30‐day post‐randomisation death/stroke compared with medical treatment alone (low certainty).

1 finding from 1 review

Endovascular therapy plus conventional medical treatment vs medical treatment

Stroke (ischaemic or haemorrhagic)Median · people with vertebral artery stenosis

Endovascular treat ment plus medical treatment showed no clear difference in stroke (ischaemic or haemorrhagic)Median compared with medical treatment alone (moderate certainty).

1 finding from 1 review