Hot flush frequency (number/day) · women with hot flushes
Transdermal beta‐estradiol patch showed no clear difference in frequency of hot flushes Beta‐estradiol patch 0.0375‐0.10 mg/day compared with placebo (low certainty).
1 finding from 1 review
Change in frequency of hot flushes from baseline to end of study · women with hot flushes
Intranasal beta‐estradiol showed no clear difference in frequency of hot flushes Change from baseline Intranasal… compared with placebo (moderate certainty).
1 finding from 1 review
Adverse effects Intranasal beta‐estradiol 0.021 mg/day, 0.029 mg/day or 0.040 mg/day · women with hot flushes
Intranasal beta‐estradiol probably leads to higher adverse effects Intranasal beta‐estradiol 0.021 mg/day, 0.029 mg/day… compared with placebo (moderate certainty).
1 finding from 1 review
Hot flush frequency (number/day) · women with hot flushes
1 finding from 1 review
Adverse events Beta‐estradiol patch 0.05 or 0.1 mg/day vs CEE 0.625 or 1.25 mg/day · women with hot flushes
1 finding from 1 review
Frequency of hot flushes Oral beta‐estradiol 1.0 and 2.0 mg/day vs CEE 0.625 or 1.25 mg/day · women with hot flushes
1 finding from 1 review
Adverse events Oral beta‐estradiol 1.0 or 2.0 mg/day vs CEE 0.625 or 1.25 mg/day · women with hot flushes
1 finding from 1 review
Intensity of hot flushes Beta‐estradiol patch 0.025‐0.05 mg/day · women with hot flushes
Transdermal beta‐estradiol patch showed no clear difference in intensity of hot flushes Beta‐estradiol patch 0.025‐0.05 mg/day compared with placebo (low certainty).
1 finding from 1 review
Adverse effects Beta‐estradiol patch dose 0.10 mg/day · women with hot flushes
Transdermal beta‐estradiol patch may leads to higher adverse effects Beta‐estradiol patch dose 0.10 mg/day compared with placebo (low certainty).
1 finding from 1 review
Hot flush frequency (number/day) · women with hot flushes
1 finding from 1 review
Adverse effects Beta‐estradiol gel dose 1.5 mg/day · women with hot flushes
1 finding from 1 review
Hot flush frequency (number/day) · women with hot flushes
Oral beta‐estradiol showed no clear difference in frequency of hot flushes Oral beta‐estradiol 0.5‐1.0 mg/day compared with placebo (low certainty).
1 finding from 1 review
Adverse effects Oral beta‐estradiol 0.5‐2.0 mg/day · women with hot flushes
1 finding from 1 review
Rate of vasomotor symptoms ‐ · women with vasomotor symptoms
1 finding from 1 review
Adverse effects Micellar nanoparticle beta‐estradiol 8.6 mg/day · women with vasomotor symptoms
Topical beta‐estradiol emulsion showed no clear difference in adverse effects Micellar nanoparticle beta‐estradiol 8.6 mg/day compared with placebo (low certainty).
1 finding from 1 review
Intervention not reported
Total duration of mechanical ventilation (days) · Neonates with PPHN
The intervention showed no clear difference in total duration of mechanical ventilation (days) (low certainty).
1 finding from 1 review
no estimate extracted
37 participants
Low
Intervention not reported
Duration of iNO therapy (days) · Neonates with PPHN
1 finding from 1 review
no estimate extracted
21 participants
Low
Intervention not reported
Total duration of mechanical ventilation (days) · Neonates with PPHN
1 finding from 1 review
no estimate extracted
21 participants
Low
Length of hospital stay · Pregnant women with hyperemesis gravidarum
1 finding from 1 review
Severity, reduction or cessation in nausea/vomiting 2.Days of hospital admission 3. Pregnancy complications 4. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found