Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Varenicline vs e‐cigarettes

Smoking abstinence at longest · people who continued to smoke tobacco following acute coronary syndrome

It is very uncertain whether varenicline changes smoking abstinence at longest compared with e‐cigarettes (very low certainty).

1 finding from 1 review

High vs low dose pegylated interferon alpha‐2a or alpha‐2b

PEG interferon alpha‐2a · patients on HD with HCV infection

High showed no clear difference in PEG interferon alpha‐2a compared with low dose pegylated interferon alpha‐2a or alpha‐2b (low certainty).

4 findings from 1 review
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High vs low dose pegylated interferon alpha‐2a or alpha‐2b

PEG interferon (alpha‐2b) · patients on HD with HCV infection

High showed no clear difference in PEG interferon alpha‐2b compared with low dose pegylated interferon alpha‐2a or alpha‐2b (low certainty).

2 findings from 1 review