Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,327 questions · 2,494 findings · 87 reviews · All outcomes

No studies found 450 · 18%GRADE not reported 1,487 · 59.6%Very low 385 · 15.4%Low 121 · 4.9%Moderate 50 · 2%High 1 · 0%

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs placebo or no treatment

Oral candidiasis (present) · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole,… led to lower oral candidiasis (present) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Antifungal drugs absorbed from GI tract (fluconazole, ketoconazole, itraconazole) vs Antifungal drugs not absorbed from GI tract

Toxicity (adverse events probably due to drug) · Patients with cancer receiving chemotherapy and/or radiotherapy

Antifungal drugs absorbed from GI tract showed no clear difference in toxicity (adverse events probably due to drug) compared with antifungal drugs not absorbed from GI tract; GRADE not reported.

1 finding from 1 review

Lingualised teeth (maxillary anatomic + mandibular non-anatomic; lingualised occlusion scheme) vs Zero-degree teeth (non-anatomic, cuspless)

Number of denture adjustments required · Edentulous adult patients requiring complete dentures
1 finding from 1 review

Lingualised teeth (maxillary anatomic + mandibular non-anatomic; lingualised occlusion scheme) vs Zero-degree teeth (non-anatomic, cuspless)

Patient perceived satisfaction (denture preference) · Edentulous adult patients requiring complete dentures

Lingualised teeth (maxillary anatomic + mandibular non-anatomic;… led to higher patient perceived satisfaction (denture preference) compared with zero-degree teeth (non-anatomic, cuspless); GRADE not reported.

1 finding from 1 review