Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,355 questions · 2,459 findings · 279 reviews

No studies found 556 · 22.6%GRADE not reported 490 · 19.9%Very low 593 · 24.1%Low 479 · 19.5%Moderate 243 · 9.9%High 98 · 4%

Multidimensional powered toothbrush vs Side to side action powered toothbrush

Plaque (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review
  • Different powered toothbrushes for plaque control and gingival health 2010 · Cochrane All outcomes
    Short term (1-3 months)
    Analysis 5.1 Plaque < 3 months (Turesky): 3 trials, 236 participants (Goyal 2005; Patters 2005; Zimmer 2005); significant heterogeneity (P < 0.1; I2 = 96%), so no statistical pooling was undertaken.
    3 studies · 236 participants
    GRADE not reported

Intervention not reported

Number commencing naltrexone maintenance treatment ‐ Clonidine comparison · patients with opioid withdrawal

The intervention probably leads to higher number commencing naltrexone maintenance treatment ‐ Clonidine… (moderate certainty).

1 finding from 1 review

Intervention not reported

Number commencing naltrexone maintenance treatment ‐ Buprenorphine comparison · patients with opioid withdrawal

The intervention probably leads to higher number commencing naltrexone maintenance treatment ‐ Buprenorphine… (moderate certainty).

1 finding from 1 review

Intervention not reported

Retained in naltrexone maintenance treatment or abstinent at 12 weeks ‐ Tapered methadone comparison · patients with opioid withdrawal

The intervention showed no clear difference in retained in naltrexone maintenance treatment or abstinent at 12… (low certainty).

1 finding from 1 review

Intervention not reported

Retained in naltrexone maintenance treatment or abstinent at 12 weeks ‐ Clonidine comparison · patients with opioid withdrawal

The intervention probably leads to higher retained in naltrexone maintenance treatment or abstinent at 12… (moderate certainty).

1 finding from 1 review

Intervention not reported

Retained in naltrexone maintenance treatment or abstinent at 12 weeks ‐ Buprenorphine comparison · patients with opioid withdrawal

The intervention showed no clear difference in retained in naltrexone maintenance treatment or abstinent at 12… (moderate certainty).

1 finding from 1 review

Intervention not reported

Participants experiencing adverse effects · patients with opioid withdrawal

The intervention probably leads to higher participants experiencing adverse effects (moderate certainty).

1 finding from 1 review

Powered toothbrush, counter oscillation action vs Circular powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review
  • Different powered toothbrushes for plaque control and gingival health 2010 · Cochrane All outcomes
    Short term (1-3 months) · Adolescents
    Trimpeneers 1997 reported a significant difference in favour of the counter oscillation brush for gingival index at 2 months over a circular mode of action brush; data were unsuitable for meta-analysis.
    1 study · 36 participants
    GRADE not reported

Powered toothbrush, side-to-side action vs Counter oscillation powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Side to side action powered toothbrush showed no clear difference in gingivitis (level reduction) compared with counter oscillation powered toothbrush; GRADE not reported.

1 finding from 1 review

Multidimensional powered toothbrush vs Side to side action powered toothbrush

Staining · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review

Powered toothbrush, rotation oscillation action vs Circular powered toothbrush

Plaque (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Rotation oscillation powered toothbrush showed no clear difference in plaque (level reduction) compared with circular powered toothbrush; GRADE not reported.

1 finding from 1 review

Powered toothbrush, side-to-side action vs Circular powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Side to side action powered toothbrush led to higher gingivitis (level reduction) compared with circular powered toothbrush; GRADE not reported.

1 finding from 1 review

Powered toothbrush, rotation oscillation action vs Circular powered toothbrush

Gingivitis (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)

Rotation oscillation powered toothbrush led to higher gingivitis (level reduction) compared with circular powered toothbrush; GRADE not reported.

1 finding from 1 review

Powered toothbrush, side-to-side action vs Circular powered toothbrush

Plaque (level reduction) · Individuals of any age with no reported disability that might affect toothbrushing (including people wearing orthodontic appliances)
1 finding from 1 review
  • Different powered toothbrushes for plaque control and gingival health 2010 · Cochrane All outcomes
    Short term (1-3 months)
    Analysis 3.1 Plaque < 3 months (Turesky): 1 trial (Yankell 1997), 64 participants; totals not selected; no significant difference between side to side and circular for plaque in the short term.
    1 study · 64 participants
    GRADE not reported

Fluoride toothpaste vs Fluoride mouthrinse

Unacceptability of treatment (drop-outs / leaving study early) · Children and adolescents aged 16 years or less

Fluoride toothpaste showed no clear difference in unacceptability of treatment (drop-outs) compared with fluoride mouthrinse; GRADE not reported.

1 finding from 1 review

Fluoride toothpaste vs Fluoride mouthrinse

Proportion of children developing new caries (permanent) · Children and adolescents aged 16 years or less

Fluoride toothpaste showed no clear difference in proportion of children developing new caries (permanent) compared with fluoride mouthrinse; GRADE not reported.

1 finding from 1 review

Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Fluoride mouthrinse

Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review