Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,345 questions · 4,525 findings · 483 reviews

No studies found 1,024 · 22.6%GRADE not reported 388 · 8.6%Very low 1,172 · 25.9%Low 1,227 · 27.1%Moderate 576 · 12.7%High 138 · 3%

Fresh frozen plasma vs no plasma

Number of participants receiving a red cell transfusion (total) · Neonates, children and adults undergoing cardiovascular surgery

Fresh frozen plasma probably leads to higher number of patients receiving a red cell transfusion compared with no plasma (moderate certainty).

1 finding from 1 review

Fresh frozen plasma vs no plasma

Resource use: need for return to theatre · Neonates, children and adults undergoing cardiovascular surgery

Fresh frozen plasma showed no clear difference in resource use: need for return to theatre compared with no plasma (moderate certainty).

1 finding from 1 review

Intervention not reported

Mortality · patients undergoing cardiac surgery

The intervention showed no clear difference in mortality (moderate certainty).

1 finding from 1 review

Intervention not reported

Myocardial infarction ECG/cardiac enzymes · patients undergoing cardiac surgery

The intervention showed no clear difference in myocardial infarction ECG/cardiac enzymes (low certainty).

1 finding from 1 review

Intervention not reported

Atrial fibrillation ECG · patients undergoing cardiac surgery

The intervention probably leads to lower atrial fibrillation ECG (moderate certainty).

1 finding from 1 review

Intervention not reported

Renal failure Serum creatinine/urea · patients undergoing cardiac surgery

The intervention showed no clear difference in renal failure Serum creatinine/urea (moderate certainty).

1 finding from 1 review

NPPV vs oxygen therapy

Duration of ICU stay · adults (aged > 17 years) with acute respiratory failure after upper abdominal surgery

It is very uncertain whether noninvasive positive pressure ventilation (NPPV) changes ICU length of stay compared with oxygen therapy (very low certainty).

1 finding from 1 review

Liberal vs restrictive transfusion protocols

Inability to walk 10 feet (3 m; or across a room) without human assistance · Patients with hip fracture repair

Liberal showed no clear difference in inability to walk 10 feet (3 m; or across a room) without human… compared with restrictive threshold transfusion (low certainty).

1 finding from 1 review