Findings

What do systematic reviews say?

2,289 questions · 2,331 findings · 195 reviews · Pregnancy and Childbirth

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No studies found 480 · 20.6%GRADE not reported 288 · 12.4%Very low 467 · 20%Low 630 · 27%Moderate 338 · 14.5%High 128 · 5.5%

Antibiotics vs placebo

Side effects · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo

Duration of admission to neonatal intensive care unit · Women with meconium‐stained amniotic fluid in labour, gestational age more than 24 weeks

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for meconium‐stained amniotic fluid in labour for preventing maternal and neonatal infections 2014 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Maternal composite morbidity · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… leads to lower maternal composite morbidity compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 0.67 [0.54, 0.82]
10 studies · 5041 participants
High

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Endomyometritis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… leads to lower maternal endomyometritis compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 0.54 [0.36, 0.79]
10 studies · 5041 participants
High

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Wound infection · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… leads to lower maternal wound Infection compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 0.59 [0.44, 0.81]
10 studies · 5041 participants
High

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Maternal UTI/cystitis/pyelonephritis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in maternal UTI/cystitis/pyelonephritis compared with after neonatal umbilical cord clamping (moderate certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 1.02 [0.65, 1.59]
8 studies · 4001 participants
Moderate

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Maternal respiratory infection (pneumonia) · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in maternal respiratory infection (pneumonia) compared with after neonatal umbilical cord clamping (low certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 2.3 [0.34, 15.45]
2 studies · 1158 participants
Low

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Neonatal sepsis · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in neonatal sepsis compared with after neonatal umbilical cord clamping (moderate certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 0.76 [0.51, 1.13]
5 studies · 2907 participants
Moderate

Prophylactic intravenous antibiotics administered before cesarean incision vs after neonatal umbilical cord clamping

Admission to neonatal intensive care unit · women undergoing caesarean section

Prophylactic intravenous antibiotics administered before cesarean… showed no clear difference in neonatal ICU admission compared with after neonatal umbilical cord clamping (high certainty).

1 finding from 1 review

Timing of intravenous prophylactic antibiotics for preventing postpartum infectious morbidity in women undergoing… 2014 · Cochrane Headline outcomes only
RR 0.91 [0.74, 1.13]
6 studies · 3708 participants
High