Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,006 questions · 3,171 findings · 607 reviews · Headline outcomes only

No studies found 411 · 13%GRADE not reported 153 · 4.8%Very low 968 · 30.5%Low 897 · 28.3%Moderate 589 · 18.6%High 153 · 4.8%

Lower blood pressure targets vs standard blood pressure targets

Total serious adverse events · cardiovascular disease with high blood pressure

Lower blood pressure targets showed no clear difference in total serious adverse events compared with standard blood pressure targets (low certainty).

1 finding from 1 review

Lower blood pressure targets vs standard blood pressure targets

Cardiovascular mortality · cardiovascular disease with high blood pressure

Lower blood pressure targets showed no clear difference in cardiovascular mortality compared with standard blood pressure targets (moderate certainty).

1 finding from 1 review

Lower blood pressure targets vs standard blood pressure targets

Withdrawals due to adverse events · cardiovascular disease with high blood pressure

It is very uncertain whether lower blood pressure targets changes participant withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty).

1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (professionals' self‐report, actual cases) Time of outcome assessment: short term (3 months postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Attitudes toward the duty to report child abuse and neglect Measured by: professionals’ self‐reported attitudes towards the duty to report child abuse and neglect Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (professionals' self‐report, hypothetical vignette cases) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Number of reported cases of child abuse and neglect (official records of reports made to child protection authorities) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Quality of reported cases of child abuse and neglect (official records of reports made to child protection authorities) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Adverse events · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of reporting duty, processes, and procedures Measured by: professionals' self‐reported knowledge of jurisdictional or institutional reporting duties, or both Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of core concepts in child abuse and neglect (all forms) Measured by: professionals' self‐reported knowledge of all forms of child abuse and neglect (general measure) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Knowledge of core concepts in child abuse and neglect (child sexual abuse only) Measured by: professionals' self‐reported knowledge of child sexual abuse (specific measure) Time of outcome assessment: short term (postintervention) · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

Child protection training for professionals to improve reporting of child abuse and neglect vs no training, waitlist control, or alternative training not related to child abuse and neglect (primary outcomes)

Skill in distinguishing between reportable and non‐reportable child abuse and neglect cases Measured by: professionals’ performance on simulated cases scored by trained and blinded expert panel Time of outcome assessment: short term (postintervent... · postqualified professionals, including elementary and high school teachers, childcare professionals, medical practitioners, nurses, and…
1 finding from 1 review

MDA vs no MDA

Parasitaemia prevalence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA showed no clear difference in parasitaemia prevalence compared with no MDA (low certainty).

1 finding from 1 review

MDA vs no MDA

Parasitaemia incidence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA probably leads to lower parasitaemia incidence compared with no MDA (moderate certainty).

1 finding from 1 review

MDA vs no MDA

Confirmed malaria illness incidence · People of all ages living in an area with moderate to high endemicity of P falciparum malaria (≥ 10% prevalence)

MDA showed no clear difference in confirmed malaria illness incidence compared with no MDA (low certainty).

1 finding from 1 review

Gemcitabine vs BCG

Time to recurrence · participants with recurrent (1‐course BCG failure) high‐risk non‐muscle invasive bladder cancer (49 men, 31 women)Country: Italy

Gemcitabine may leads to lower time to recurrence compared with BCG (low certainty).

1 finding from 1 review