What do systematic reviews say?

Tenofovir‐based antiviral combination regimens vs placebo or tenofovir alone or non‐tenofovir‐based antiviral regimens

It is very uncertain whether tenofovir‐based antiviral combination regimens changes all‐cause infant mortality at longest compared with placebo or tenofovir alone or non‐tenofovir‐based antiviral regimens (very low certainty).

• Antivirals for prevention of hepatitis B virus mother‐to‐child transmission in human immunodeficiency virus positive… 2023 · Cochrane Headline outcomes only
  RR 2.24 [0.72, 6.96]
  1 study · 132 participants
  Very low

Tenofovir‐based antiviral combination regimens vs placebo or tenofovir alone or non‐tenofovir‐based antiviral regimens

It is very uncertain whether tenofovir‐based antiviral combination regimens changes proportion of infants with serious adverse events ( compared with placebo or tenofovir alone or non‐tenofovir‐based antiviral regimens (very low certainty).

• Antivirals for prevention of hepatitis B virus mother‐to‐child transmission in human immunodeficiency virus positive… 2023 · Cochrane Headline outcomes only
  RR 1.76 [1.27, 2.43]
  1 study · 132 participants
  Very low

Tenofovir‐based antiviral combination regimens vs placebo or tenofovir alone or non‐tenofovir‐based antiviral regimens

• Antivirals for prevention of hepatitis B virus mother‐to‐child transmission in human immunodeficiency virus positive… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Tenofovir‐based antiviral combination regimens vs placebo or tenofovir alone or non‐tenofovir‐based antiviral regimens

• Antivirals for prevention of hepatitis B virus mother‐to‐child transmission in human immunodeficiency virus positive… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Tenofovir‐based antiviral combination regimens vs placebo or tenofovir alone or non‐tenofovir‐based antiviral regimens

It is very uncertain whether tenofovir‐based antiviral combination regimens changes proportion of mothers with serious adverse events ( compared with placebo or tenofovir alone or non‐tenofovir‐based antiviral regimens (very low certainty).

• Antivirals for prevention of hepatitis B virus mother‐to‐child transmission in human immunodeficiency virus positive… 2023 · Cochrane Headline outcomes only
  RR 0.9 [0.62, 1.32]
  2 studies · 270 participants
  Very low

Continuous positive airway pressure (CPAP) plus best supportive care vs supportive care

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Variable flow vs bubble CPAP

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Variable flow vs bubble CPAP

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Infant Flow CPAP vs continuous positive airway pressure (CPAP)

It is very uncertain whether infant Flow CPAP changes failed CPAP compared with medijet CPAP (very low certainty).

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  RR 2.62 [0.91, 7.53]
  1 study · 80 participants
  Very low

Infant Flow CPAP vs continuous positive airway pressure (CPAP)

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  24 participants
  GRADE not reported

Infant Flow CPAP vs continuous positive airway pressure (CPAP)

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  2
  2 participants
  GRADE not reported

Infant Flow CPAP vs continuous positive airway pressure (CPAP)

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Continuous positive airway pressure (CPAP) plus best supportive care vs supportive care

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Continuous positive airway pressure (CPAP) plus best supportive care vs supportive care

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Continuous positive airway pressure (CPAP) plus best supportive care vs supportive care

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Variable flow vs ventilator CPAP

It is very uncertain whether variable flow changes failed CPAP (defined as need for mechanical ventilation) compared with ventilator CPAP (very low certainty).

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  RR 0.16 [0.01, 2.9]
  1 study · 26 participants
  Very low

Variable flow vs ventilator CPAP

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 26 participants
  Very low

Variable flow vs ventilator CPAP

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Variable flow vs bubble CPAP

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Variable flow vs bubble CPAP

The review found no eligible studies for this question.

• Continuous positive airway pressure (CPAP) for apnoea of prematurity 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found