Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Regular‐dose postoperative 5‐Fluorouracil vs control

Complications ‐ wound leak ‐ high risk of failure · participants with glaucoma surgery

Regular‐dose postoperative 5‐Fluorouracil probably leads to higher complications ‐ wound leak ‐ high risk of failure compared with control (moderate certainty).

1 finding from 1 review

Combined oral and intravenous vs oral or intravenous alone

Wound infection · colorectal surgery

Combined oral and intravenous leads to lower surgical wound infection: oral + iv versus iv alone compared with oral or intravenous alone (high certainty).

2 findings from 1 review