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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,105 questions in 84 reviews · Metabolic and Endocrine Disorders
current versionsNo studies 434 · 39.3%Ungraded 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Laparoscopic retroperitoneal adrenalectomy vs laparoscopic transperitoneal adrenalectomy Early morbidity (any complication during the first 30 to 60 days following surgery) Transperitoneal versus retroperitoneal laparoscopic adrenalectomy for adrenal tumours in adults (2018) · Cochrane | RR 0.56 [0.27, 1.16] | 5 studies · 244 participants | Very low |
Laparoscopic retroperitoneal adrenalectomy vs laparoscopic transperitoneal adrenalectomy Late morbidity (any complication following surgery at latest available Transperitoneal versus retroperitoneal laparoscopic adrenalectomy for adrenal tumours in adults (2018) · Cochrane | RR 0.12 [0.01, 0.92] | 3 studies · 146 participants | Very low |
Laparoscopic retroperitoneal adrenalectomy vs laparoscopic transperitoneal adrenalectomy Health‐related quality of life Transperitoneal versus retroperitoneal laparoscopic adrenalectomy for adrenal tumours in adults (2018) · Cochrane | no estimate extracted | NR | No studies |
Laparoscopic retroperitoneal adrenalectomy vs laparoscopic transperitoneal adrenalectomy Socioeconomic effects a. Time to return to normal activities b. Time to ambulation c. Length of hospital stay Transperitoneal versus retroperitoneal laparoscopic adrenalectomy for adrenal tumours in adults (2018) · Cochrane | no estimate extracted | 3 studies · 102 participants | Very low |
Intervention NR 1 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | NR | Moderate |
Intervention NR 10 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 23 participants | Moderate |
Intervention NR 11 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | NR | Moderate |
Intervention NR 12 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 31 participants | Moderate |
Intervention NR 15 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | NR | Moderate |
Intervention NR 20 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | NR | Moderate |
Summary of findings: risk of intermediate hyperglycaemia (IFG5.6 mmol/L definition) vs normoglycaemia HR: 4 IRR: 6 OR: 10 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 2385 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IFG5.6 mmol/L definition) vs normoglycaemia HR: 3 IRR: 3 OR: 9 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 5685 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IFG5.6 mmol/L definition) vs normoglycaemia HR: 0 IRR: 0 OR: 1 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 0 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IFG5.6 mmol/L definition) vs normoglycaemia HR: 1 IRR: 1 OR: 1 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 947 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IFG5.6 mmol/L definition) vs normoglycaemia HR: 8 IRR: 10 OR: 21 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 9017 participants | Low |
Intervention NR 2 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 2 participants | Moderate |
Summary of findings: risk of intermediate hyperglycaemia (IFG6.1 mmol/L definition) vs normoglycaemia HR: 5 IRR: 2 OR: 7 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 1054 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IFG6.1 mmol/L definition) vs normoglycaemia HR: 4 IRR: 4 OR: 7 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 1736 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IFG6.1 mmol/L definition) vs normoglycaemia HR: 0 IRR: 0 OR: 1 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 0 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IFG6.1 mmol/L definition) vs normoglycaemia HR: 0 IRR: 0 OR: 0 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 0 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IFG6.1 mmol/L definition) vs normoglycaemia HR: 9 IRR: 6 OR: 15 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 2818 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IGT definition) vs normoglycaemia HR: 3 IRR: 5 OR: 6 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 1780 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IGT definition) vs normoglycaemia HR: 2 IRR: 5 OR: 11 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 2230 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IGT definition) vs normoglycaemia HR: 0 IRR: 0 OR: 2 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 0 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IGT definition) vs normoglycaemia IRR: 2 OR: 1 HR: 0 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 1087 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (IGT definition) vs normoglycaemia HR: 5 IRR: 12 OR: 20 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 4010 participants | Low |
Intervention NR 3 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 17 participants | Moderate |
Summary of findings: risk of intermediate hyperglycaemia (combined IFG and IGT definition) vs normoglycaemia HR: 3 IRR: 4 OR: 3 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 461 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (combined IFG and IGT definition) vs normoglycaemia HR: 1 IRR: 4 OR: 6 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 221 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (combined IFG and IGT definition) vs normoglycaemia HR: 0 IRR: 0 OR: 0 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 0 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (combined IFG and IGT definition) vs normoglycaemia HR: 1 IRR: 1 OR: 0 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 356 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (combined IFG and IGT definition) vs normoglycaemia HR: 5 IRR: 9 OR: 9 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 1038 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c5.7 definition) vs normoglycaemia HR: 3 IRR: 1 OR: 1 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 3196 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c5.7 definition) vs normoglycaemia HR: 1 IRR: 0 OR: 2 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 2027 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c5.7 definition) vs normoglycaemia HR: 0 IRR: 0 OR: 0 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 0 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c5.7 definition) vs normoglycaemia HR: 4 IRR: 1 OR: 3 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 5223 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c6.0 definition) vs normoglycaemia HR: 2 IRR: 0 OR: 1 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 1040 participants | Low |
Intervention NR 4 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 17 participants | Moderate |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c6.0 definition) vs normoglycaemia HR: 4 IRR: 0 OR: 1 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 3492 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c6.0 definition) vs normoglycaemia HR: 0 IRR: 0 OR: 0 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 0 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c6.0 definition) vs normoglycaemia IRR: 0 OR: 1 HR: 0 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 0 participants | Low |
Summary of findings: risk of intermediate hyperglycaemia (HbA1c6.0 definition) vs normoglycaemia HR: 6 IRR: 0 OR: 3 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 4532 participants | Low |
Intervention NR 5 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 18 participants | Moderate |
Intervention NR 6 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 22 participants | Moderate |
Intervention NR 7 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 18 participants | Moderate |
Intervention NR 8 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 34 participants | Moderate |
Intervention NR 9 Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia (2018) · Cochrane | no estimate extracted | 38 participants | Moderate |
Short‐acting insulin analogues vs regular human insulin All‐cause mortality (N) Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2… (2018) · Cochrane | Peto OR 1.66 [0.41, 6.64] | 6 studies · 2519 participants | Moderate |
Short‐acting insulin analogues vs regular human insulin Macrovascular or microvascular complications Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2… (2018) · Cochrane | no estimate extracted | NR | No studies |
Short‐acting insulin analogues vs regular human insulin Severe hypoglycaemic episodes (N) Short‐acting insulin analogues versus regular human insulin for adult, non‐pregnant persons with type 2… (2018) · Cochrane | no estimate extracted | 6 studies · 2509 participants | Low |