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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Population

Intervention or exposure

Comparison

Outcome

Any field or review title

Field or topic

Source

Review versions

2,206 questions in 117 reviews · Common Mental Disorders

current versions

No studies 387 · 17.5%Ungraded 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Question	Effect	Evidence	Status / GRADE
Intervention NR sertraline:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR vilazodone:sertraline · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR vortioxetine:sertraline · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR vilazodone:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR vortioxetine:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR sertraline:citalopram · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR vilazodone:vortioxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR citalopram:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR desvenlafaxine:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR duloxetine:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR escitalopram:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR fluoxetine:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR mirtazapine:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR paroxetine:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR sertraline:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR venlafaxine:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR citalopram:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR vilazodone:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR vortioxetine:placebo · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR citalopram:vilazodone · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR citalopram:vortioxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR duloxetine:desvenlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR escitalopram:desvenlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR mirtazapine:desvenlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR paroxetine:desvenlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR sertraline:desvenlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR fluoxetine:duloxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR venlafaxine:desvenlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR vilazodone:desvenlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR desvenlafaxine:vortioxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR duloxetine: escitalopram · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	High
Intervention NR duloxetine:mirtazapine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR duloxetine:paroxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR sertraline:duloxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR duloxetine:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR duloxetine:vilazodone · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR duloxetine:vortioxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR fluoxetine:vilazodone · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR fluoxetine:escitalopram · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	High
Intervention NR escitalopram:mirtazapine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR escitalopram:paroxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR sertraline:escitalopram · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR escitalopram:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR escitalopram:vilazodone · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR escitalopram:vortioxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low
Intervention NR fluoxetine:mirtazapine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR fluoxetine:paroxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR sertraline:fluoxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Moderate
Intervention NR fluoxetine:vortioxetine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Very low
Intervention NR fluoxetine:venlafaxine · children and/or adolescents with depression New generation antidepressants for depression in children and adolescents: a network meta‐analysis (2021) · Cochrane	no estimate extracted	NR	Low