Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound

Adverse events (partial loss of movement, algodystrophic syndrome) · patients with trigger finger

It is very uncertain whether open surgery changes adverse events (partial loss of movement, algodystrophic syndrome) compared with steroid injection plus hyaluronic acid injection guided by ultrasound (very low certainty).

1 finding from 1 review

Open surgery vs steroid injection

Participant global assessment of success Not measured · patients with trigger finger

The review found no eligible studies for this question.

1 finding from 1 review

Open surgery vs steroid injection

Recurrence · patients with trigger finger

Open surgery may leads to lower recurrence compared with steroid injection (low certainty).

1 finding from 1 review

Open surgery vs steroid injection

Adverse events (infection, tendon or pulley injury, flare, cutaneous discomfort, fat necrosis) · patients with trigger finger

Open surgery showed no clear difference in adverse events (infection, tendon or pulley injury, flare, cutaneous… compared with steroid injection (low certainty).

1 finding from 1 review

Open surgery vs steroid injection

Neurovascular injury · patients with trigger finger

Open surgery showed no clear difference in neurovascular injury compared with steroid injection (low certainty).

1 finding from 1 review

Surgery fee waiver with/without transport provision or reimbursement to improve access to cataract surgical services vs usual care

Service utilisation: uptake of surgery · people with vision impairment caused by cataract

Surgery fee waiver with/without transport provision or reimbursement… may leads to higher service utilisation: uptake of surgery compared with standard care (low certainty).

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Cataract surgery with Hydrus microstent probably leads to higher proportion of participants who were medication‐free (not using eye… compared with cataract surgery alone (moderate certainty).

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry medium‐term · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Glaucoma progression at 12 months, measured by additional visual field defects · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Cataract surgery with Hydrus microstent vs cataract surgery alone

Mean change in health‐related quality of life · people with cataracts and open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Computer‐assisted reconstruction surgery vs conventional operating techniques

IKDC knee examination grade normal (grade A) or nearly normal (grade B) ‐ Intermediate/long‐term · People, primarily adults, undergoing ACL reconstruction surgery

Computer‐assisted reconstruction surgery showed no clear difference in IKDC knee examination grade normal (grade A) or nearly normal (grade… compared with conventional operating techniques (low certainty).

1 finding from 1 review

Surgery plus whole brain radiotherapy (WBRT) vs stereotactic radiosurgery

Overall survival · people with single or solitary brain metastasis

It is very uncertain whether surgery plus whole brain radiotherapy (WBRT) changes overall survival compared with stereotactic radiosurgery (very low certainty).

1 finding from 1 review