Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

322 questions · 324 findings · 25 reviews · Eyes and Vision

No studies found 77 · 23.8%GRADE not reported 5 · 1.5%Very low 77 · 23.8%Low 64 · 19.8%Moderate 91 · 28.1%High 10 · 3.1%

Tocilizumab every 4 weeks vs placebo

Proportion of participants who did not need escape therapy (as defined by study investigators) · adults aged over 50 years with giant cell arteritis

The review found no eligible studies for this question.

1 finding from 1 review

Tocilizumab every 4 weeks vs placebo

Mean change in quality of life at ≥ 12 months using the 36‐Item Short Form Health Survey mental component score (SF‐36 MCS) · adults aged over 50 years with giant cell arteritis

The review found no eligible studies for this question.

1 finding from 1 review

Tocilizumab every 4 weeks vs placebo

Mean change in VAS (higher scores suggest greater disease activity and worse quality of life) at ≥ 12 months · adults aged over 50 years with giant cell arteritis

The review found no eligible studies for this question.

1 finding from 1 review

Oral antibiotics vs placebo

Measurements of eradication or decrease in numbers of colonies of positive cultures of bacteria · adult participants with chronic blepharitis

The review found no eligible studies for this question.

1 finding from 1 review