Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

285 questions · 327 findings · 36 reviews · Headline outcomes only

No studies found 129 · 39.4%GRADE not reported 11 · 3.4%Very low 82 · 25.1%Low 64 · 19.6%Moderate 38 · 11.6%High 3 · 0.9%

Intervention not reported

Deep surgical site infection at 30 days or 90 days, or time points reported by study authors · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Adverse events: superficial infection · adults with open long bone fractures; study in the review included only Gustilo II open tibia fractures

It is very uncertain whether the intervention changes adverse events: superficial infection (very low certainty).

1 finding from 1 review

Phaco‐AIT vs Phaco‐Trab

Proportion of participants who were medication‐free (not using drops) at 12 months · people with open‐angle glaucoma

It is very uncertain whether phaco‐AIT changes proportion of participants who were medication‐free (not using… compared with phaco‐Trab (very low certainty).

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Glaucoma progression at 12 months, measured by additional visual field defects · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Mean change in health‐related quality of life · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

The review found no eligible studies for this question.

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Proportion of participants who were medication‐free (not using eye drops) short‐term · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication

Hydrus microstent may leads to higher proportion of participants who were medication‐free (not using eye… compared with iStent trabecular micro‐bypass stent (low certainty).

1 finding from 1 review

Hydrus microstent vs iStent trabecular micro‐bypass stent

Mean change in unmedicated IOP (after washout) measured using Goldmann applanation tonometry short‐term · people with open angle glaucoma, many of whom had mild or moderate glaucoma, which was well‐controlled with medication
1 finding from 1 review