Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

541 questions · 556 findings · 112 reviews · Headline outcomes only

No studies found 130 · 23.4%GRADE not reported 22 · 4%Very low 156 · 28.1%Low 151 · 27.2%Moderate 72 · 12.9%High 25 · 4.5%

Setting of BP measurement: self‐measurement vs conventional clinic measurement

Maternal admission to intensive care · pregnant women with chronic or gestational hypertension

Setting of BP measurement: self‐measurement showed no clear difference in maternal admission to intensive care compared with conventional clinic measurement (low certainty).

1 finding from 1 review

Hypnotherapy vs behavioural treatments or no treatment

Smoking cessation · people who smoke

It is very uncertain whether hypnotherapy changes hypnotherapy versus intensive behavioural interventions (not matched… compared with behavioural treatments or no treatment (very low certainty).

1 finding from 1 review

Metformin vs diet and exercise or another antidiabetic drug

Intensive diet plus exercise · people at increased risk for developing type 2 diabetes
4 findings from 1 review
Show 1 more finding

Metformin vs diet and exercise or another antidiabetic drug

Intensive diet plus exercise Diagnostic criteria: 1 trial applied the WHO 1985 criteria (FPG < 7.8 mmol/L and 2‐hour glucose ≥ 7.8 mmol/L and < 11.1 mmol/L) (Fang 2004) · people at increased risk for developing type 2 diabetes

Summary of findings table for metformin showed no clear difference in intensive diet plus exercise Diagnostic criteria: 1 trial applied… compared with diet and exercise or another antidiabetic drug (moderate certainty).

1 finding from 1 review

Any antihypertensive drug vs no antihypertensive drugs/placebo

Admission to neonatal or intensive care nursery · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in admission to neonatal or intensive care nursery compared with no antihypertensive drugs/placebo (low certainty).

1 finding from 1 review

Intervention not reported

Maternal admission to intensive care · pregnant women

The intervention showed no clear difference in maternal admission to intensive care (low certainty).

1 finding from 1 review

Perioperative alcohol cessation intervention vs treatment

Postoperative complications after perioperative intervention (e.g. wound‐related complications, secondary surgery, cardiopulmonary complications, admission to intensive care) defined by need for treatment · adult surgical patients consuming 3 or more units of alcohol per day

Perioperative alcohol cessation intervention probably leads to lower postoperative complications after perioperative intervention (e.g.… compared with treatment (moderate certainty).

1 finding from 1 review