Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

257 questions · 270 findings · 42 reviews · Headline outcomes only

No studies found 75 · 27.8%GRADE not reported 7 · 2.6%Very low 95 · 35.2%Low 50 · 18.5%Moderate 40 · 14.8%High 3 · 1.1%

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

Medication given before LTP showed no clear difference in IOP increase of ≥ 5 mmHg between 2 and 24 hours compared with the same medication given after LTP (moderate certainty).

1 finding from 1 review

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

It is very uncertain whether medication given before LTP changes IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with the same medication given after LTP (very low certainty).

1 finding from 1 review