Maternal infectious morbidity (chorioamnionitis and/or endometritis) · women with prelabour rupture of membranes at term (37 weeks' gestation or later)
Planned early birth may leads to lower maternal infectious morbidity (chorioamnionitis and/or endometritis) compared with expectant management (low certainty).
1 finding from 1 review
Caesarean section · women with prelabour rupture of membranes at term (37 weeks' gestation or later)
Planned early birth showed no clear difference in caesarean section compared with expectant management (low certainty).
1 finding from 1 review
Serious maternal morbidity or death · women with prelabour rupture of membranes at term (37 weeks' gestation or later)
1 finding from 1 review
Perinatal mortality · women with prelabour rupture of membranes at term (37 weeks' gestation or later)
Planned early birth showed no clear difference in perinatal mortality (stillbirth or neonatal mortality) compared with expectant management (moderate certainty).
1 finding from 1 review
Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth
Twice-yearly 38% SDF was reported to arrest more caries than once-yearly application (24-month rates 91% vs 79%; ungraded).
1 finding from 1 review
Chronic lung disease · preterm infants
Very early treatment showed no clear difference in chronic lung disease compared with expectant management (low certainty).
1 finding from 1 review
Severe intraventricular hemorrhage in infants who received neuroimaging · preterm infants
Very early treatment showed no clear difference in severe Intraventricular hemorrhage (grades III and IV) compared with expectant management (moderate certainty).
1 finding from 1 review
NEC ≥ stage II · preterm infants
Very early treatment showed no clear difference in necrotizing enterocolitis (NEC; stage 2 or greater) compared with expectant management (moderate certainty).
1 finding from 1 review
Duration of hospitalization · preterm infants
1 finding from 1 review
Neurodevelopmental outcomes (moderate/severe cognitive delay at 18 to 24 months) · preterm infants
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe cognitive delay at 18… compared with expectant management (low certainty).
1 finding from 1 review
Neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24 months) · preterm infants
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24… compared with expectant management (low certainty).
1 finding from 1 review
Neurodevelopmental outcomes (moderate/severe language delay at 18 to 24 months) · preterm infants
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe language delay at 18 to… compared with expectant management (low certainty).
1 finding from 1 review
All‐cause mortality during hospital stay · preterm infants
Very early treatment showed no clear difference in all‐cause mortality during hospital stay compared with expectant management (moderate certainty).
1 finding from 1 review
Proportion of infants requiring surgical PDA ligation or transcatheter occlusion · preterm infants
Very early treatment showed no clear difference in proportion of infants requiring surgical PDA ligation or… compared with expectant management (moderate certainty).
1 finding from 1 review
Proportion of infants receiving any pharmacotherapy for a hemodynamically significant PDA · preterm infants
It is very uncertain whether very early treatment changes proportion of infants receiving any pharmacotherapy for a… compared with expectant management (very low certainty).
1 finding from 1 review
Incidence of incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in incidence of incisal trauma compared with early treatment (two-phase) with functional appliance; GRADE not reported.
2 findings from 1 review
Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in final ANB compared with early treatment (two-phase) with functional appliance; GRADE not reported.
2 findings from 1 review
PAR score · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in PAR score compared with early treatment (two-phase) with functional appliance; GRADE not reported.
1 finding from 1 review
Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)
Early treatment (two-phase) with headgear showed no clear difference in final overjet compared with early treatment (two-phase) with functional appliance; GRADE not reported.
2 findings from 1 review
Maternal mortality or morbidity · pregnant women with hypertensive disorders from 34 weeks' gestation to term
Planned early delivery leads to lower composite maternal mortality and morbidity compared with expectant management (high certainty).
1 finding from 1 review