Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

343 questions · 360 findings · 49 reviews

No studies found 95 · 26.4%GRADE not reported 16 · 4.4%Very low 45 · 12.5%Low 121 · 33.6%Moderate 76 · 21.1%High 7 · 1.9%

Lanolin vs expressed breast milk

Nipple pain Women's reports of 'absence of irritation' · breastfeeding women with sore nipples

Lanolin showed no clear difference in nipple pain Women's reports of 'absence of irritation' compared with expressed breast milk (low certainty).

3 findings from 1 review

Lanolin vs no intervention

Nipple pain 5‐point verbal descriptor scale · breastfeeding women with sore nipples

Lanolin showed no clear difference in nipple pain 5‐point verbal descriptor scale compared with no intervention (control group) (low certainty).

3 findings from 1 review

Expressed breast milk vs no intervention

Nipple pain 5‐point verbal descriptor scale · breastfeeding women with sore nipples

Expressed breast milk showed no clear difference in nipple pain 5‐point verbal descriptor scale compared with no intervention (control group) (low certainty).

3 findings from 1 review

Probiotics vs placebo

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Probiotics may leads to lower incidence of mastitis within 6 months postpartum compared with placebo (low certainty).

1 finding from 1 review

Antibiotics vs topical treatments

Incidence of mastitis within 6 months postpartum · postpartum breastfeeding women

Antibiotics showed no clear difference in incidence of mastitis within 6 months postpartum ‐ Antibiotics… compared with topical treatments (low certainty).

2 findings from 1 review