Findings

What do systematic reviews say?

217 questions · 259 findings · 23 reviews

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No studies found 55 · 21.2%GRADE not reported 17 · 6.6%Very low 50 · 19.3%Low 40 · 15.4%Moderate 69 · 26.6%High 28 · 10.8%

High dose BoNT‐A vs Low dose BoNT‐A

Wrist flexor spasticity · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 1 participants
GRADE not reported

High dose BoNT‐A vs Low dose BoNT‐A

Quality of movement (18 mths ‐ 8yrs) Quality of Upper Extremity Skills Test. Scale from: 0 to 100. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Moderate

High dose BoNT‐A vs Low dose BoNT‐A

Goal attainment Goal Attainment Scaling3. Scale from: 20 to 80. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 1 participants
GRADE not reported

BoNT‐A vs placebo/no treatment

Quality of movement (5 yrs ‐ 15yrs) The Melbourne Assessment. Scale from: 0 to 100. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 21 participants
Moderate

High dose BoNT‐A vs Low dose BoNT‐A

Quality of movement (5 yrs ‐ 15yrs) The Melbourne Assessment. Scale from: 0 to 100. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 1 participants
GRADE not reported

High dose BoNT‐A vs Low dose BoNT‐A

Occupational performance ‐ performance Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 1 participants
GRADE not reported

High dose BoNT‐A vs Low dose BoNT‐A

Occupational performance ‐ satisfaction Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 1 participants
GRADE not reported

BoNT‐A vs placebo/no treatment

Goal attainment Goal Attainment Scaling3. Scale from: 20 to 80. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Moderate

BoNT‐A vs placebo/no treatment

Occupational performance ‐ performance Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
High

BoNT‐A vs placebo/no treatment

Occupational performance ‐ satisfaction Canadian Occupational Performance Measure. Scale from: 0 to 10. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
High

BoNT‐A/OT vs OT only

Elbow flexor spasticity modified Tardieu scale. Scale from: 0 to 180. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
High

BoNT‐A/OT vs OT only

Wrist flexor spasticity modified Tardieu scale. Scale from: 0 to 90. · children with cerebral palsy

1 finding from 1 review

Botulinum toxin A as an adjunct to treatment in the management of the upper limb in children with spastic cerebral… 2010 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
High

Intervention not reported

Pain (0‐10 cm visual analog scale)‐ Pain at 6‐12 weeks Visual Analog or Verbal Rating Scale. Scale from: 0 to 10. ( · patients with shoulder pain

1 finding from 1 review

Botulinum toxin for shoulder pain 2010 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 76 participants
Low

Intervention not reported

Number of Adverse Events (AEs) ( · patients with shoulder pain

The intervention showed no clear difference in number of Adverse Events (AEs) ( (low certainty).

1 finding from 1 review

Botulinum toxin for shoulder pain 2010 · Cochrane Headline outcomes only
RR 1.46 [0.64, 3.36]
3 studies · 65 participants
Low

Intervention not reported

Disability/function ‐ not reported · patients with shoulder pain

The review found no eligible studies for this question.

1 finding from 1 review

Botulinum toxin for shoulder pain 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

WIthdrawals due to Adverse Events ‐ not reported · patients with shoulder pain

The review found no eligible studies for this question.

1 finding from 1 review

Botulinum toxin for shoulder pain 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Serious Adverse Events ‐ not reported · patients with shoulder pain

The review found no eligible studies for this question.

1 finding from 1 review

Botulinum toxin for shoulder pain 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found