Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

213 questions · 219 findings · 19 reviews

No studies found 25 · 11.4%GRADE not reported 33 · 15.1%Very low 70 · 32%Low 64 · 29.2%Moderate 18 · 8.2%High 9 · 4.1%

Benzodiazepines vs placebo

Alcohol withdrawal seizures objective · people with alcohol withdrawal

Benzodiazepine probably leads to lower alcohol withdrawal seizures objective compared with placebo (moderate certainty).

1 finding from 1 review

Benzodiazepines vs placebo

Adverse events · people with alcohol withdrawal

Benzodiazepine showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Benzodiazepines vs placebo

Leaving the study early · people with alcohol withdrawal

Benzodiazepine showed no clear difference in dropouts compared with placebo (moderate certainty).

1 finding from 1 review

Benzodiazepines vs Other Drug for

Alcohol withdrawal seizures ‐ Benzodiazepine vs. Other Drug · patients with

Benzodiazepine showed no clear difference in alcohol withdrawal seizures ‐ Benzodiazepine vs. Other Drug compared with other Drug for (moderate certainty).

1 finding from 1 review

Benzodiazepines vs Other Drug for

Alcohol withdrawal seizures ‐ Benzodiazepine vs. Anticonvulsant · patients with

Benzodiazepine showed no clear difference in alcohol withdrawal seizures ‐ Benzodiazepine vs. Anticonvulsant compared with other Drug for (moderate certainty).

1 finding from 1 review

Benzodiazepines vs Other Drug for

Adverse events ‐ Benzodiazepine vs. Other Drug · patients with

Benzodiazepine showed no clear difference in adverse events ‐ Benzodiazepine vs. Other Drug compared with other Drug for (low certainty).

1 finding from 1 review

Benzodiazepines vs Other Drug for

Adverse events ‐ Benzodiazepine vs. Anticonvulsant · patients with

Benzodiazepine showed no clear difference in adverse events ‐ Benzodiazepine vs. Anticonvulsant compared with other Drug for (high certainty).

1 finding from 1 review

Benzodiazepines vs Other Drug for

Dropouts ‐ Benzodiazepine vs. Other Drug · patients with

Benzodiazepine showed no clear difference in dropouts ‐ Benzodiazepine vs. Other Drug compared with other Drug for (moderate certainty).

1 finding from 1 review

Benzodiazepines vs Other Drug for

Dropouts ‐ Benzodiazepine vs. Anticonvulsant · patients with

Benzodiazepine showed no clear difference in dropouts ‐ Benzodiazepine vs. Anticonvulsant compared with other Drug for (high certainty).

1 finding from 1 review