Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,511 questions · 2,668 findings · 290 reviews

No studies found 743 · 27.8%GRADE not reported 329 · 12.3%Very low 775 · 29%Low 484 · 18.1%Moderate 279 · 10.5%High 58 · 2.2%

Azithromycin + SRP vs SRP

Adverse events · Adults with periodontitis (chronic and aggressive)

It is very uncertain whether azithromycin + SRP changes adverse events compared with SRP (very low certainty).

1 finding from 1 review

Amoxicillin + metronidazole + SRP vs SRP

Adverse events · Adults with periodontitis (chronic and aggressive)

It is very uncertain whether amoxicillin + metronidazole + SRP changes adverse events compared with SRP (very low certainty).

1 finding from 1 review

Levofloxacin + SRP vs SRP

Clinical attachment level (CAL) · Adults with chronic periodontitis

Levofloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.

2 findings from 1 review

Triangular flap vs Envelope flap

Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal

It is very uncertain whether triangular flap changes permanent altered tongue, chin, or lip sensation compared with envelope flap (very low certainty).

1 finding from 1 review

Lingual nerve retractor (subperiosteal or Free's) vs No retractor

Permanent altered tongue, chin, or lip sensation · Adults with mandibular third molars requiring removal

It is very uncertain whether lingual nerve retractor (subperiosteal or Free's) changes permanent altered tongue, chin, or lip sensation compared with no retractor (very low certainty).

1 finding from 1 review