Number of participants with ≥ 1 AE ‐ week 4 · people with scabies, 5 to 80 years of ageLocation: India
It is very uncertain whether topical ivermectin 1% lotion (1 to 3 applications) changes number of participants with ≥ 1 AE ‐ week 4 compared with topical permethrin 5% cream (1 to 3 applications) (very low certainty).
1 finding from 1 review
Number of participants with ≥ 1 AE ‐ week 2 · people with scabies, 2 to 80 years of ageLocation: India, Pakistan
1 finding from 1 review
Number of participants with ≥ 1 AE ‐ week 4 · people with scabies, 2 to 80 years of ageLocation: India, Pakistan
Oral ivermectin 200 μg/kg (1 to 3 doses) showed no clear difference in number of participants with ≥ 1 AE ‐ week 4 compared with topical permethrin 5% cream (1 to 3 applications) (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with scabies, 2 to 80 years of ageLocation: India, Pakistan
1 finding from 1 review
Intervention not reported
Leukopenia** grade 3 or 4 (safety population) · women with metastatic breast cancer
The intervention probably leads to higher leukopenia** grade 3 or 4 (safety population) (moderate certainty).
1 finding from 1 review
Intervention not reported
Overall survival ‐ trials of mTNBC participants · women with metastatic triple‐negative breast cancer (mTNBC)
The intervention showed no clear difference in overall survival ‐ trials of mTNBC participants (low certainty).
1 finding from 1 review
Intervention not reported
Progression‐free survival/time to progression (randomised participants) ‐ trials of mTNBC participants · women with metastatic triple‐negative breast cancer (mTNBC)
The intervention may leads to lower progression‐free survival/time to progression (randomised… (low certainty).
1 finding from 1 review
Intervention not reported
Objective tumour response rate (assessable participants) ‐ trials of mTNBC participants · women with metastatic triple‐negative breast cancer (mTNBC)
The intervention may leads to higher objective tumour response rate (assessable participants) ‐ trials of… (low certainty).
1 finding from 1 review
Intervention not reported
Nausea/vomiting* grade 3 or 4 (safety population) by type of platinum agent in platinum regimen · women with metastatic breast cancer
The intervention probably leads to lower nausea/vomiting* grade 3 or 4 (safety population) by type of… (moderate certainty).
1 finding from 1 review
Intervention not reported
Anaemia grade 3 or 4 (safety population) by type of platinum agent in platinum regimen · women with metastatic breast cancer
The intervention leads to higher anaemia grade 3 or 4 (safety population) by type of platinum agent… (high certainty).
1 finding from 1 review
Intervention not reported
Hair loss grade 3 or 4 (safety population) · women with metastatic breast cancer
The intervention leads to higher hair loss grade 3 or 4 (safety population) (high certainty).
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · women with endometriosis
It is very uncertain whether NSAID changes pain relief compared with placebo (very low certainty).
1 finding from 1 review
Unintended effects from treatment · women with endometriosis
It is very uncertain whether NSAID changes unintended effects from treatment compared with placebo (very low certainty).
1 finding from 1 review
Quality of life: not reported · women with endometriosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Restriction of daily life activities ‐ not reported · women with endometriosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Absence from work or school: not reported · women with endometriosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of women requiring more invasive treatment: not reported · women with endometriosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Requirement for additional medication · women with endometriosis
It is very uncertain whether NSAID changes requirements for additional medication compared with placebo (very low certainty).
1 finding from 1 review
Participant satisfaction with treatment: not reported · women with endometriosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Overall survival · Patients with brain metastases
Whole brain radiation therapy (WBRT) + stereotactic radiosurgery (SRS) showed no clear difference in overall survival compared with WBRT (moderate certainty).
1 finding from 1 review