Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Summary of findings: Molecular‐targeted therapy plus chemotherapy vs chemotherapy alone

Overall response rate Duration of · people with advanced gastric cancer

Summary of findings: Molecular‐targeted therapy plus chemotherapy showed no clear difference in overall response rate Duration of compared with chemotherapy alone (low certainty).

1 finding from 1 review

Summary of findings: Molecular‐targeted therapy plus chemotherapy vs chemotherapy alone

Adverse event (any) Duration of · people with advanced gastric cancer

Summary of findings: Molecular‐targeted therapy plus chemotherapy probably leads to higher adverse event (any) Duration of compared with chemotherapy alone (moderate certainty).

1 finding from 1 review

Summary of findings: Molecular‐targeted therapy plus chemotherapy vs chemotherapy alone

Severe adverse event (grade ≥ 3 ) Duration of · people with advanced gastric cancer

Summary of findings: Molecular‐targeted therapy plus chemotherapy probably leads to higher severe adverse event (grade ≥ 3 ) Duration of compared with chemotherapy alone (moderate certainty).

1 finding from 1 review

Percutaneous endoscopic gastrostomy vs nasogastric tube feeding

Treatment failure Feeding interruption, blocking or leakage of the tube, non‐adherence · adult patients with swallowing disturbances

Percutaneous endoscopic gastrostomy may leads to lower treatment failure Feeding interruption, blocking or leakage of the… compared with nasogastric tube feeding (low certainty).

1 finding from 1 review

Percutaneous endoscopic gastrostomy vs nasogastric tube feeding

Mortality irrespective of · adult patients with swallowing disturbances

It is very uncertain whether percutaneous endoscopic gastrostomy changes mortality irrespective of compared with nasogastric tube feeding (very low certainty).

1 finding from 1 review

Percutaneous endoscopic gastrostomy vs nasogastric tube feeding

Adverse events irrespective of · adult patients with swallowing disturbances

Percutaneous endoscopic gastrostomy showed no clear difference in adverse events irrespective of compared with nasogastric tube feeding (moderate certainty).

1 finding from 1 review

Etanercept vs placebo

Percentage of participants reaching PASI 75 · people with paediatric psoriasis

Etanercept leads to higher PASI 75 Participants achieving a 75% improvement in the Psoriasis… compared with placebo (high certainty).

1 finding from 1 review

Etanercept vs placebo

PASI 50 · people with paediatric psoriasis

Etanercept leads to higher PASI 50 Participants achieving a 50% improvement in the Psoriasis… compared with placebo (high certainty).

1 finding from 1 review

Etanercept vs placebo

PASI 90 · people with paediatric psoriasis

Etanercept leads to higher PASI 90 Participants achieving a 90% improvement in the Psoriasis… compared with placebo (high certainty).

1 finding from 1 review