What do systematic reviews say?

Condiments/seasonings fortified with iron plus other micronutrients vs condiments/seasonings fortified with other micronutrients except iron

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Condiments/seasonings fortified with iron vs unfortified condiments/seasonings

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 2808 participants
  Very low

Condiments/seasonings fortified with iron vs unfortified condiments/seasonings

Condiments/seasonings fortified with iron showed no clear difference in iron deficiency (as defined by the trialists based on a biomarker of… compared with unfortified condiments/seasonings (moderate certainty).

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  RR 0.33 [0.11, 1.01]
  2 studies · 391 participants
  Moderate

Condiments/seasonings fortified with iron vs unfortified condiments/seasonings

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 4459 participants
  Very low

Condiments/seasonings fortified with iron vs unfortified condiments/seasonings

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 240 participants
  Low

Condiments/seasonings fortified with iron vs unfortified condiments/seasonings

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 240 participants
  Low

Condiments/seasonings fortified with iron vs unfortified condiments/seasonings

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Condiments/seasonings fortified with iron plus other micronutrients vs condiments/seasonings fortified with other micronutrients except iron

Condiments/seasonings fortified with iron plus other micronutrients may leads to lower anaemia (defined as haemoglobin below WHO cut‐off for age and… compared with condiments/seasonings fortified with other micronutrients except iron (low certainty).

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  RR 0.59 [0.4, 0.89]
  4 studies · 1007 participants
  Low

Condiments/seasonings fortified with iron plus other micronutrients vs condiments/seasonings fortified with other micronutrients except iron

• Fortification of condiments and seasonings with iron for preventing anaemia and improving health 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 1270 participants
  Very low

Amlodipine plus standard iron chelation therapy vs standard chelation therapy with or without placebo

• Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion‐dependent beta… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 191 participants
  Low

Amlodipine plus standard iron chelation therapy vs standard chelation therapy with or without placebo

• Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion‐dependent beta… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 138 participants
  Low

Amlodipine plus standard iron chelation therapy vs standard chelation therapy with or without placebo

• Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion‐dependent beta… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 136 participants
  Low

Amlodipine plus standard iron chelation therapy vs standard chelation therapy with or without placebo

• Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion‐dependent beta… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 187 participants
  Low

Amlodipine plus standard iron chelation therapy vs standard chelation therapy with or without placebo

• Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion‐dependent beta… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 127 participants
  Low

Amlodipine plus standard iron chelation therapy vs standard chelation therapy with or without placebo

• Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion‐dependent beta… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 123 participants
  Moderate

Amlodipine plus standard iron chelation therapy vs standard chelation therapy with or without placebo

• Calcium channel blockers for preventing cardiomyopathy due to iron overload in people with transfusion‐dependent beta… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 234 participants
  Very low

Atraumatic restorative treatment with GIC vs Conventional restoration

ART with GIC was reported to increase the odds of restoration failure versus conventional restoration (OR 1.60; ungraded).

• Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: an umbrella review. 2022 All outcomes

  12-24 months
  OR 1.60 [1.13, 2.27]
  6 studies · 1107 participants
  GRADE not reported

Aspirin vs placebo

Aspirin showed no clear difference in total mortality compared with placebo (low certainty).

• Antiplatelet agents and anticoagulants for hypertension 2022 · Cochrane Headline outcomes only
  OR 0.97 [0.87, 1.08]
  3 studies · 35794 participants
  Low

Aspirin vs placebo

Aspirin showed no clear difference in cardiovascular mortality compared with placebo (low certainty).

• Antiplatelet agents and anticoagulants for hypertension 2022 · Cochrane Headline outcomes only
  OR 0.98 [0.82, 1.17]
  3 studies · 35794 participants
  Low

Aspirin vs placebo

Aspirin may leads to lower non‐fatal cardiovascular events compared with placebo (low certainty).

• Antiplatelet agents and anticoagulants for hypertension 2022 · Cochrane Headline outcomes only
  OR 0.63 [0.45, 0.87]
  1 study · 2540 participants
  Low