What do systematic reviews say?

Intervention not reported

The review found no eligible studies for this question.

• Interventions for treating acute high altitude illness 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Interventions for treating acute high altitude illness 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 64 participants
  Low

Intervention not reported

• Interventions for treating acute high altitude illness 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 29 participants
  Low

Intervention not reported

The review found no eligible studies for this question.

• Interventions for treating acute high altitude illness 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Interventions for treating acute high altitude illness 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 35 participants
  Low

Intervention not reported

The intervention showed no clear difference in reduction in symptom score severity Time of measurement: 1 to 48… (low certainty).

• Interventions for treating acute high altitude illness 2018 · Cochrane Headline outcomes only
  Mean Difference 1.15
  2 studies · 25 participants
  Low

Intervention not reported

• Interventions for treating acute high altitude illness 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Low

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Lower showed no clear difference in mortality, near term corrected age or discharge compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

• Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm… 2018 · Cochrane Headline outcomes only
  RR 1.05 [0.68, 1.63]
  10 studies · 914 participants
  Low

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Lower showed no clear difference in neurodevelopmental disability compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

• Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm… 2018 · Cochrane Headline outcomes only
  RR 0.82 [0.49, 1.35]
  2 studies · 208 participants
  Low

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Lower showed no clear difference in intubation in the delivery room compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

• Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm… 2018 · Cochrane Headline outcomes only
  RR 0.98 [0.82, 1.18]
  9 studies · 875 participants
  Low

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Lower showed no clear difference in severe retinopathy of prematurity (≥ stage 3) compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

• Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm… 2018 · Cochrane Headline outcomes only
  RR 0.57 [0.24, 1.36]
  4 studies · 453 participants
  Low

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Lower showed no clear difference in severe intraventricular haemorrhage (grade 3 or 4) compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

• Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm… 2018 · Cochrane Headline outcomes only
  RR 0.93 [0.51, 1.71]
  6 studies · 596 participants
  Low

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

Lower showed no clear difference in necrotising enterocolitis compared with higher oxygen concentrations titrated to target oxygen saturations… (low certainty).

• Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm… 2018 · Cochrane Headline outcomes only
  RR 0.98 [0.51, 1.87]
  8 studies · 807 participants
  Low

Lower vs higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm infants at birth

It is very uncertain whether lower changes chronic lung disease (36 weeks' corrected age) compared with higher oxygen concentrations titrated to target oxygen saturations… (very low certainty).

• Lower versus higher oxygen concentrations titrated to target oxygen saturations during resuscitation of preterm… 2018 · Cochrane Headline outcomes only
  RR 0.91 [0.72, 1.14]
  9 studies · 862 participants
  Very low

Sumatriptan vs placebo

Sumatriptan may leads to lower risk of acute mountain sickness compared with placebo (low certainty).

• Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes only
  RR 0.43 [0.21, 0.84]
  1 study · 102 participants
  Low

Spironolactone vs placebo

The review found no eligible studies for this question.

• Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Acetazolamide vs spironolactone 100 mg

Acetazolamide may leads to lower risk of acute mountain sickness compared with spironolactone (low certainty).

• Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes only
  RR 0.36 [0.18, 0.7]
  1 study · 232 participants
  Low

Acetazolamide vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Sumatriptan vs placebo

The review found no eligible studies for this question.

• Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Magnesium citrate vs placebo

Magnesium citrate showed no clear difference in risk of acute mountain sickness compared with placebo (low certainty).

• Interventions for preventing high altitude illness: Part 2. Less commonly‐used drugs 2018 · Cochrane Headline outcomes only
  RR 1.09 [0.55, 2.13]
  1 study · 70 participants
  Low