Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Endovenous laser ablation (EVLA) vs conventional surgery

Recurrence · people requiring intervention for short saphenous vein varices

Endovenous laser ablation showed no clear difference in clinical evidence of recurrence after 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Endovenous laser ablation (EVLA) vs conventional surgery

Disease‐specific quality of life · people requiring intervention for short saphenous vein varices
2 findings from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recanalisation or persistence of reflux at 6 weeks · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recanalisation or persistence of reflux at 6 weeks compared with conventional surgery (low certainty).

1 finding from 1 review

Ultrasound‐guided foam sclerotherapy vs conventional surgery

Recurrence of reflux at 1 year · people requiring intervention for short saphenous vein varices

Ultrasound‐guided foam sclerotherapy showed no clear difference in recurrence of reflux at 1 year compared with conventional surgery (low certainty).

1 finding from 1 review

Intervention not reported

Successful cannulation at the first attempt · paediatric patients

The intervention probably leads to higher successful cannulation at the first attempt (moderate certainty).

1 finding from 1 review

Intervention not reported

Rate of complications (haematoma or ischaemia) · paediatric patients

The intervention probably leads to lower rate of complications (haematoma or ischaemia) (moderate certainty).

1 finding from 1 review

Intervention not reported

Successful cannulation within the first 2 attempts · paediatric patients

The intervention probably leads to higher successful cannulation within the first 2 attempts (moderate certainty).

1 finding from 1 review

Summary of findings: Molecular‐targeted therapy plus chemotherapy vs chemotherapy alone

Progression‐free survival · people with advanced gastric cancer

Summary of findings: Molecular‐targeted therapy plus chemotherapy showed no clear difference in progression‐free survival compared with chemotherapy alone (low certainty).

1 finding from 1 review