Findings

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Evidence found and GRADE certainty

4,760 questions · 8,065 findings · 1,036 reviews

No studies found 1,686 · 20.9%GRADE not reported 675 · 8.4%Very low 1,953 · 24.2%Low 2,048 · 25.4%Moderate 1,296 · 16.1%High 407 · 5%

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Intervention not reported

Presence of PDA on third to fourth day of life (after 72 hours of treatment) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life

The intervention probably leads to lower presence of PDA on third to fourth day of life (after 72 hours of… (moderate certainty).

1 finding from 1 review

Intervention not reported

Need for surgical closure of PDA (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life

The intervention probably leads to lower need for surgical closure of PDA (during hospital stay) (moderate certainty).

1 finding from 1 review

Intervention not reported

Presence of PDA on day 3 or 4 of life (after 72 hours of treatment) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life

The intervention may leads to lower presence of PDA on day 3 or 4 of life (after 72 hours of treatment) (low certainty).

1 finding from 1 review

Intervention not reported

Time to achieve full enteral feeding (days) · preterm infants with low birth weight

The intervention showed no clear difference in time to achieve full enteral feeding (days) (low certainty).

1 finding from 1 review

Intervention not reported

Cerebral palsy at 18 to 24 months' corrected age · preterm infants with low birth weight

The intervention showed no clear difference in cerebral palsy at 18 to 24 months' corrected age (high certainty).

1 finding from 1 review

Intervention not reported

BSID‐III composite cognitive scores at 18 to 22 months The Bayley‐III has 3 main sub tests: the Cognitive Scale, which includes items such as attention to familiar and unfamiliar objects, looking for a fallen object, and pretend play; the Language... · neonates born preterm with low birth weight

The intervention probably leads to higher BSID‐III composite cognitive scores at 18 to 22 months The… (moderate certainty).

1 finding from 1 review

Intervention not reported

WPPSI‐III FSIQ at 3.5 to 4 years of age Composite scores have a mean of 100 and a standard deviation of 15. Average is 90 to 109. · neonates born preterm with low birth weight

The intervention may leads to higher WPPSI‐III FSIQ at 3.5 to 4 years of age Composite scores have a mean… (low certainty).

1 finding from 1 review

Intervention not reported

Any neurodevelopmental impairment at 18 to 22 months' corrected age (in children examined) · preterm infants with low birth weight

The intervention may leads to lower any neurodevelopmental impairment at 18 to 22 months' corrected age… (low certainty).

1 finding from 1 review