Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,447 questions · 2,590 findings · 266 reviews

No studies found 699 · 27%GRADE not reported 289 · 11.2%Very low 614 · 23.7%Low 605 · 23.4%Moderate 322 · 12.4%High 61 · 2.4%

Testosterone vs other active intervention

Miscarriage · women undergoing assisted reproduction

It is very uncertain whether testosterone changes miscarriage ‐ Testosterone vs estradiol compared with other active interventions (very low certainty).

2 findings from 1 review

Testosterone vs other active intervention

Clinical pregnancy rate ‐ Testosterone vs estradiol · women undergoing assisted reproduction

It is very uncertain whether testosterone changes clinical pregnancy rate ‐ Testosterone vs estradiol compared with other active interventions (very low certainty).

1 finding from 1 review

Summary of findings: whole‐body cryotherapy (WBC) vs control (no WBC or passive rest)

Muscle pain at rest · physically‐active adults partaking in exercise designed to produce delayed onset muscle soreness (most trial participants were male)

It is very uncertain whether summary of findings: whole‐body cryotherapy (WBC) changes muscle soreness: pain at rest (VAS) compared with control (no WBC or passive rest) (very low certainty).

4 findings from 1 review
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Summary of findings: whole‐body cryotherapy (WBC) vs control (no WBC or passive rest)

Adverse events · physically‐active adults partaking in exercise designed to produce delayed onset muscle soreness (most trial participants were male)

The review found no eligible studies for this question.

1 finding from 1 review

Home‐based vs clinic‐based specimen collection

Index case management (6 to 12 weeks of · Sexually active people

Home‐based showed no clear difference in index case management (6 to 12 weeks of compared with clinic‐based specimen collection (moderate certainty).

1 finding from 1 review

ITI SLA standard (regular neck) implants vs ITI SLActive implants

Implant failure · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

ITI SLA standard (regular neck) implants showed no clear difference in implant failure compared with ITI SLActive implants; GRADE not reported.

1 finding from 1 review