Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,922 questions · 3,118 findings · 513 reviews

No studies found 574 · 18.4%GRADE not reported 372 · 11.9%Very low 723 · 23.2%Low 854 · 27.4%Moderate 489 · 15.7%High 106 · 3.4%

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)

Serious adverse events: cardiovascular events · older adults with primary hypertension

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in cardiovascular serious adverse events compared with lower BP target (< 140/90 mmHg) (low certainty).

1 finding from 1 review

Dopamine vs norepinephrine

Total mortalitya · hypotensive shock

Dopamine showed no clear difference in total mortalitya compared with norepinephrine (high certainty).

1 finding from 1 review

Terlipressin vs norepinephrine

Total mortalitya · hypotensive shock

It is very uncertain whether terlipressin changes total mortalitya compared with norepinephrine (very low certainty).

1 finding from 1 review

Vasopressin vs norepinephrine

Total mortalitya · hypotensive shock

Vasopressin showed no clear difference in total mortalitya compared with norepinephrine (moderate certainty).

1 finding from 1 review

Phenylephrine vs norepinephrine

Total mortalitya · hypotensive shock

It is very uncertain whether phenylephrine changes total mortalitya compared with norepinephrine (very low certainty).

1 finding from 1 review