Intervention not reported
Anatomic form success rate
1 finding from 1 review
Whitening (bleaching) efficacy · Demineralised / white-spot-lesion enamel (in vitro specimens)
Low-quality in vitro evidence indicates that adding fluoride or other remineralising agents does not impair the whitening/bleaching effect (ungraded).
1 finding from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between GG genotype vs AA genotype of LTF rs1126478 and dental caries susceptibility (GG vs AA model: OR 0.97, 95% CI 0.73-1.29) in the Ethnicity: Asian subgroup; certainty not graded.
5 findings from 1 review
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Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between TT genotype vs CC genotype of AMELX rs17878486 and dental caries susceptibility (TT vs CC model: OR 5.12, 95% CI 0.09-278.85) in the Control group: Caries-free subgroup; certainty not graded.
8 findings from 1 review
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Caries incidence (proportion of enrolled children developing dentin caries, ICDAS 4-6) · Generally healthy children aged 6 to 9 years with at least one fully erupted first permanent molar with deep fissures or early enamel…
Fluoride varnish and fissure sealant did not differ significantly in the proportion of children developing caries at 2 to 3 years (RR 1.12, 95% CI 0.60 to 2.09; 2 RCTs; ungraded).
1 finding from 1 review
Dental caries susceptibility · Ethnicity: Asian (n=1) individuals with caries/high caries and controls
The pooled odds ratio was 0.33 (95% CI 0.01 to 12.82).
1 finding from 1 review
OR 0.33 [0.01, 12.82]
1 study
GRADE not reported
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between CT + TT genotype (T-allele carriers) vs CC genotype of AMELX rs2106416 and dental caries susceptibility (CT + TT vs CC model: OR 0.59, 95% CI 0.15-2.31) in the Age group: Children subgroup; certainty not graded.
3 findings from 1 review
Colour change / camouflage of white spot lesions (reduction of colour disparity between carious and sound enamel) · Permanent teeth with post-orthodontic white spot lesions (orthodontic patients and in vitro enamel specimens)
Bleaching may diminish colour disparities and camouflage post-orthodontic white spot lesions, but the certainty of the evidence is very low; the findings could neither support nor refute bleaching.
1 finding from 1 review
Enamel microhardness / caries susceptibility · Permanent teeth / enamel specimens (in vitro)
Low-quality in vitro evidence found no support for adding lasers to in-office bleaching; laser-activated bleaching did not appear to affect enamel microhardness or caries risk versus conventional bleaching (ungraded).
1 finding from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between G allele vs A allele of LTF rs1126478 and dental caries susceptibility (G vs A model: OR 0.98, 95% CI 0.87-1.10); certainty not graded.
5 findings from 1 review
Show 2 more findings
Intervention not reported
Anatomic form success rate
1 finding from 1 review
Intervention not reported
Marginal integrity success rate
1 finding from 1 review
DMFT/DMFS index (dental caries experience) · People who use drugs (PWUD): methamphetamine, heroin, opiate, cannabis and cocaine users
Illicit drug use was associated with substantially higher odds of dental caries experience (DMFT) (pooled OR 4.11, 95% CI 2.07-8.15; 7 studies; high heterogeneity I2=90.5%; ungraded).
1 finding from 1 review
Dental caries susceptibility · Ethnicity: Caucasian (n=2) individuals with caries/high caries and controls
The pooled odds ratio was 0.73 (95% CI 0.19 to 2.87).
1 finding from 1 review
OR 0.73 [0.19, 2.87]
2 studies
GRADE not reported
Intervention not reported
Absence of recurrent caries success rate
1 finding from 1 review
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between T allele vs C allele of AMELX rs17878486 and dental caries susceptibility (T vs C model: OR 2.87, 95% CI 0.35-23.23) in the Control group: Caries-free subgroup; certainty not graded.
8 findings from 1 review
Show 5 more findings
Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
No significant association between CT genotype vs CC genotype of AMELX rs2106416 and dental caries susceptibility (CT vs CC model: OR 1.20, 95% CI 0.65-2.22) in the Ethnicity: Caucasian subgroup; certainty not graded.
3 findings from 1 review
Intervention not reported
Marginal integrity success rate
1 finding from 1 review
Intervention not reported
Anatomic form success rate
1 finding from 1 review
Salivary osmolality (hydration level) · Patients with drooling (sialorrhea) due to neurological disease
No included study reported salivary osmolality; this pre-planned outcome remains unassessed (no studies).
1 finding from 1 review