Findings

What do systematic reviews say?

2,908 questions · 3,101 findings · 509 reviews

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No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Planned early birth vs expectant management

Caesarean section · pregnant women with hypertensive disorders from 34 weeks' gestation to term

Planned early delivery showed no clear difference in caesarean section compared with expectant management (moderate certainty).

1 finding from 1 review

Planned early delivery versus expectant management for hypertensive disorders from 34 weeks gestation to term 2017 · Cochrane Headline outcomes only
RR 0.91 [0.78, 1.07]
4 studies · 1728 participants
Moderate

Planned early birth vs expectant management

Maternal postpartum hospital stay (days) · pregnant women with hypertensive disorders from 34 weeks' gestation to term

1 finding from 1 review

Planned early delivery versus expectant management for hypertensive disorders from 34 weeks gestation to term 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 925 participants
Moderate

Planned early birth vs expectant management

Duration of hospital stay after delivery for baby (days) · pregnant women with hypertensive disorders from 34 weeks' gestation to term

1 finding from 1 review

Planned early delivery versus expectant management for hypertensive disorders from 34 weeks gestation to term 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 756 participants
Moderate

Glue vs suture

Chronic pain · patients with recurrence and pain in Lichtenstein inguinal hernioplasty

Glue may leads to lower chronic pain compared with suture (low certainty).

1 finding from 1 review

Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty 2017 · Cochrane Headline outcomes only
OR 0.63 [0.44, 0.91]
10 studies · 1473 participants
Low

Glue vs suture

Hernia recurrence · patients with recurrence and pain in Lichtenstein inguinal hernioplasty

Glue showed no clear difference in hernia recurrence compared with suture (low certainty).

1 finding from 1 review

Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty 2017 · Cochrane Headline outcomes only
OR 1.44 [0.63, 3.28]
12 studies · 1987 participants
Low

Glue vs suture

Duration of operation (mins) · patients with recurrence and pain in Lichtenstein inguinal hernioplasty

1 finding from 1 review

Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1790 participants
Low

Glue vs suture

Wound/superficial infection · patients with recurrence and pain in Lichtenstein inguinal hernioplasty

Glue showed no clear difference in wound/superficial infection compared with suture (low certainty).

1 finding from 1 review

Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty 2017 · Cochrane Headline outcomes only
OR 1.23 [0.37, 4.11]
7 studies · 818 participants
Low

Glue vs suture

Mesh/deep infection · patients with recurrence and pain in Lichtenstein inguinal hernioplasty

Glue showed no clear difference in mesh/deep infection compared with suture (low certainty).

1 finding from 1 review

Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty 2017 · Cochrane Headline outcomes only
OR 0.67 [0.16, 2.83]
8 studies · 1448 participants
Low

Glue vs suture

Haematoma (proportion of participants in each group with haematoma; · patients with recurrence and pain in Lichtenstein inguinal hernioplasty

Glue probably leads to lower haematoma compared with suture (moderate certainty).

1 finding from 1 review

Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty 2017 · Cochrane Headline outcomes only
OR 0.52 [0.31, 0.86]
10 studies · 1439 participants
Moderate

Glue vs suture

Time away from normal activities (days) · patients with recurrence and pain in Lichtenstein inguinal hernioplasty

1 finding from 1 review

Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 403 participants
Low

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)

All‐cause mortality · older adults with primary hypertension

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in all‐cause mortality compared with lower BP target (< 140/90 mmHg) (low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in older adults 2017 · Cochrane Headline outcomes only
RR 1.24 [0.99, 1.54]
3 studies · 8221 participants
Low

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)

Stroke · older adults with primary hypertension

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in stroke compared with lower BP target (< 140/90 mmHg) (low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in older adults 2017 · Cochrane Headline outcomes only
RR 1.25 [0.94, 1.67]
3 studies · 8221 participants
Low

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)

Serious adverse events: cardiovascular events · older adults with primary hypertension

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in cardiovascular serious adverse events compared with lower BP target (< 140/90 mmHg) (low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in older adults 2017 · Cochrane Headline outcomes only
RR 1.19 [0.98, 1.45]
3 studies · 8221 participants
Low

Higher BP target (< 150‐160/95‐105 mmHg) vs lower BP target (< 140/90 mmHg)

Withdrawals due to adverse events · older adults with primary hypertension

Higher BP target (< 150‐160/95‐105 mmHg) showed no clear difference in withdrawals due to adverse effects compared with lower BP target (< 140/90 mmHg) (low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in older adults 2017 · Cochrane Headline outcomes only
RR 0.83 [0.58, 1.19]
2 studies · 7497 participants
Low

Aspirin 1000 mg vs placebo

Pain‐free at 2 hours · adults with episodic tension‐type headache

1 finding from 1 review

Aspirin for acute treatment of episodic tension‐type headache in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Aspirin 1000 mg vs placebo

Pain‐free at different time points (1, 4, 24 hours) · adults with episodic tension‐type headache

1 finding from 1 review

Aspirin for acute treatment of episodic tension‐type headache in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Aspirin 1000 mg vs placebo

Pain‐free or mild pain at 2 hours · adults with episodic tension‐type headache

1 finding from 1 review

Aspirin for acute treatment of episodic tension‐type headache in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 215 participants
Very low

Aspirin 1000 mg vs placebo

Use of rescue medication · adults with episodic tension‐type headache

1 finding from 1 review

Aspirin for acute treatment of episodic tension‐type headache in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 397 participants
Low

Aspirin 1000 mg vs placebo

Patient Global Evaluation at end of study · adults with episodic tension‐type headache

1 finding from 1 review

Aspirin for acute treatment of episodic tension‐type headache in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 397 participants
Very low

Aspirin 1000 mg vs placebo

Any adverse event · adults with episodic tension‐type headache

1 finding from 1 review

Aspirin for acute treatment of episodic tension‐type headache in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 723 participants
Low