Surgery ‐ within 30 days · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment showed no clear difference in surgery ‐ within 30 days compared with H2RA, placebo or no treatment (low certainty).
1 finding from 1 review
Proportion of participants with stigmata of recent haemorrhage at index endoscopy · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment showed no clear difference in proportion of participants with stigmata of recent haemorrhage at… compared with H2RA, placebo or no treatment (low certainty).
1 finding from 1 review
Endoscopic haemostatic treatment at index endoscopy · people with upper gastrointestinal bleeding prior to endoscopic diagnosis
Proton pump inhibitor treatment probably leads to lower endoscopic haemostatic treatment at index endoscopy compared with H2RA, placebo or no treatment (moderate certainty).
1 finding from 1 review
50% or greater reduction in seizure frequency · people with drug‐resistant focal epilepsy
Pregabalin may leads to higher 50% or greater reduction in seizure frequency ‐ ITT analysis compared with placebo (low certainty).
3 findings from 1 review
RR 1.95 [1.4, 2.72]
9 studies · 2663 participants
Low
RR 2.91 [1.92, 4.42]
9 studies · 2663 participants
Very low
RR 1.1 [0.92, 1.31]
9 studies · 2663 participants
Very low
Adverse effects: headache · people with drug‐resistant focal epilepsy
It is very uncertain whether pregabalin changes adverse effect: headache compared with placebo (very low certainty).
1 finding from 1 review
Nausea · people with drug‐resistant focal epilepsy
Pregabalin showed no clear difference in adverse effect: nausea compared with placebo (low certainty).
1 finding from 1 review
Somnolence · people with drug‐resistant focal epilepsy
Pregabalin may leads to higher adverse effect: somnolence compared with placebo (low certainty).
1 finding from 1 review
Weight gain · people with drug‐resistant focal epilepsy
Pregabalin may leads to higher adverse effect: weight gain compared with placebo (low certainty).
1 finding from 1 review
Seizure freedom · people with drug‐resistant focal epilepsy
1 finding from 1 review
Treatment withdrawal · people with drug‐resistant focal epilepsy
Pregabalin probably leads to higher treatment withdrawal for any reason compared with placebo (moderate certainty).
1 finding from 1 review
Withdrawals due to adverse events · people with drug‐resistant focal epilepsy
Pregabalin probably leads to higher treatment withdrawal due to adverse effects compared with placebo (moderate certainty).
1 finding from 1 review
Ataxia · people with drug‐resistant focal epilepsy
Pregabalin may leads to higher adverse effect: ataxia compared with placebo (low certainty).
1 finding from 1 review
Dizziness · people with drug‐resistant focal epilepsy
Pregabalin may leads to higher adverse effect: dizziness compared with placebo (low certainty).
1 finding from 1 review
Adverse effect: fatigue · people with drug‐resistant focal epilepsy
Pregabalin showed no clear difference in adverse effect: fatigue compared with placebo (low certainty).
1 finding from 1 review
Disease severity · children aged up to 16 years with ARTIs
1 finding from 1 review
Adverse events · children aged up to 16 years with ARTIs
It is very uncertain whether homeopathic medicinal products (non‐individualised treatment) changes adverse events compared with placebo or usual care (very low certainty).
1 finding from 1 review
Short‐term cure1 · children aged up to 16 years with ARTIs
It is very uncertain whether homeopathic medicinal products changes short‐term cure1 compared with placebo or usual care (very low certainty).
1 finding from 1 review
Long‐term cure1 · children aged up to 16 years with ARTIs
It is very uncertain whether homeopathic medicinal products changes long‐term cure1 compared with placebo or usual care (very low certainty).
1 finding from 1 review
Disease severity( · children aged up to 16 years with ARTIs
1 finding from 1 review
Recurrence of ARTI · children aged up to 16 years with ARTIs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found