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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Lietofix cream vs iodoform dressing
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
RR 8.06 [1.05, 61.68]1 study · 205 participantsLow
Lietofix cream vs iodoform dressing
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Lietofix cream vs iodoform dressing
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Lietofix cream vs iodoform dressing
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Topical negative pressure wound therapy vs conventional open wound healing
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
RR 3.6 [0.49, 26.54]1 study · 19 participantsVery low
Lietofix cream vs iodoform dressing
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Lietofix cream vs iodoform dressing
Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extracted1 study · 205 participantsUngraded
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Time to wound healing (days) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extracted1 study · 31 participantsVery low
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressing vs wound cleaning with 10% povidone iodine
Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
RR 2.13 [0.22, 21.17]1 study · 31 participantsVery low
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Time to wound healing (days) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extracted2 studies · 210 participantsLow
Topical negative pressure wound therapy vs conventional open wound healing
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Platelet‐rich plasma gel vs absorbent sterile cotton gauze
Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Time to wound healing (days) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extracted1 study · 50 participantsVery low
Gentamicin‐impregnated collagen sponge vs no dressing
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Topical negative pressure wound therapy vs conventional open wound healing
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Gentamicin‐impregnated collagen sponge vs no dressing
Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing
Time to wound healing (days) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extracted1 study · 246 participantsLow
Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing
Proportion of wounds healed at 25 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
RR 0.51 [0.05, 5.53]1 study · 246 participantsVery low
Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing
Proportion of wounds healed at 6 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing
Proportion of wounds healed at 12 months · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Dialkylcarbamoyl chloride (DACC)‐coated dressing vs alginate dressing
Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Topical negative pressure wound therapy vs conventional open wound healing
Cost‐effectiveness (assessed using quality‐adjusted life years) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Topical negative pressure wound therapy vs conventional open wound healing
Pain at first postoperative dressing change (measured using a validated scale such as a visual analogue scale) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extractedNRNo studies
Topical negative pressure wound therapy vs conventional open wound healing
Adverse effects (surgical site infection or allergic reaction) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extracted2 studies · 68 participantsUngraded
Zinc oxide mesh vs placebo mesh
Time to wound healing (days) · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
no estimate extracted54 participantsLow
Zinc oxide mesh vs placebo mesh
Proportion of wounds healed at 30 days · adults with open wounds after surgery for sacrococcygeal pilonidal sinus disease
Dressings and topical agents for the management of open wounds after surgical treatment for sacrococcygeal… (2022) · Cochrane
RR 2.35 [0.49, 11.23]1 study · 64 participantsVery low
NPWT vs the Bogota bag
Time to primary fascial closure of the abdomen · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
MD 3.61 study · 40 participantsVery low
Suprasorb CNP system vs the ABThera system
Participant health‐related quality of life · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
no estimate extractedNRNo studies
NPWT vs the Bogota bag
Proportion of participants with successful primary fascial closure of the abdomen · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
no estimate extractedNRNo studies
NPWT vs the Bogota bag
Adverse events (fistulae formation) · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
RR 2 [0.2, 20.33]1 study · 40 participantsVery low
NPWT vs the Bogota bag
All‐cause mortality · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
RR 0.71 [0.27, 1.88]1 study · 40 participantsVery low
NPWT vs the Bogota bag
Participant health‐related quality of life · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
no estimate extractedNRNo studies
Suprasorb CNP system vs the ABThera system
Time to primary fascial closure of the abdomen · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
no estimate extractedNRNo studies
Suprasorb CNP system vs the ABThera system
Proportion of participants with successful primary fascial closure of the abdomen · adults with an open abdomen after surgery who have not experienced trauma
Negative pressure wound therapy for managing the open abdomen in non‐trauma patients (2022) · Cochrane
RR 0.8 [0.56, 1.14]1 study · 34 participantsVery low