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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

780 questions in 55 reviews · Public Health

current versions
No studies 162 · 20.8%Ungraded 52 · 6.7%Very low 231 · 29.6%Low 191 · 24.5%Moderate 122 · 15.6%High 22 · 2.8%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Staple foods fortified with vitamin A vs same unfortified staple foods
Subclinical vitamin A deficiency (serum/plasma retinol 70 μmol/L or less) · general population above 2 years of age
Fortification of staple foods with vitamin A for vitamin A deficiency (2019) · Cochrane
RR 0.45 [0.19, 1.05]2 studies · 993 participantsVery low
Staple foods fortified with vitamin A vs same unfortified staple foods
Clinical vitamin A deficiency (defined as night blindness) · general population above 2 years of age
Fortification of staple foods with vitamin A for vitamin A deficiency (2019) · Cochrane
RR 0.11 [0.01, 1.98]1 study · 581 participantsVery low
Staple foods fortified with vitamin A vs same unfortified staple foods
All‐cause mortality · general population above 2 years of age
Fortification of staple foods with vitamin A for vitamin A deficiency (2019) · Cochrane
no estimate extractedNRNo studies
Staple foods fortified with vitamin A vs same unfortified staple foods
All‐cause morbidity · general population above 2 years of age
Fortification of staple foods with vitamin A for vitamin A deficiency (2019) · Cochrane
no estimate extractedNRNo studies
Staple foods fortified with vitamin A vs same unfortified staple foods
Any adverse effects (e.g. hypervitaminosis A, as defined by the trialists) · general population above 2 years of age
Fortification of staple foods with vitamin A for vitamin A deficiency (2019) · Cochrane
no estimate extractedNRNo studies
Staple foods fortified with vitamin A plus other micronutrients vs same unfortified staple foods
Serum/plasma retinol (μmol/L) · general population over 2 years of age
Fortification of staple foods with vitamin A for vitamin A deficiency (2019) · Cochrane
no estimate extracted4 studies · 1009 participantsLow
Staple foods fortified with vitamin A plus other micronutrients vs same unfortified staple foods
Subclinical vitamin A deficiency (serum/plasma retinol 0.70 μmol/L or less) · general population over 2 years of age
Fortification of staple foods with vitamin A for vitamin A deficiency (2019) · Cochrane
RR 0.27 [0.16, 0.49]3 studies · 923 participantsModerate
Staple foods fortified with vitamin A plus other micronutrients vs same unfortified staple foods
Clinical vitamin A deficiency (as defined by night blindness) · general population over 2 years of age
Fortification of staple foods with vitamin A for vitamin A deficiency (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Death (all‐cause) · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Mental development · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cognitive function and motor skill development · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Cretinism · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Hypothyroidism · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse effects (RCT) · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted1 study · 33 participantsLow
Intervention NR
Urinary iodine concentration (RCT) · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted6 studies · 2032 participantsModerate
Intervention NR
Urinary iodine concentration (non‐RCT) · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted262 participantsVery low
Intervention NR
Thyroid‐stimulating hormone concentration · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Serum thyroglobulin concentration · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Goitre prevalence (RCT) · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted1 study · 1 participantsVery low
Intervention NR
Goitre prevalence (non‐RCT) · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
OR 1.6 [0.6, 4.31]83 participantsVery low
Intervention NR
Physical development measures (non‐RCT) · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extractedNRNo studies
Intervention NR
a. Weight · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted83 participantsVery low
Intervention NR
b. Height assessment tool not reported · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted83 participantsVery low
Intervention NR
c. Weight‐for‐age computed from weight and age values · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted83 participantsVery low
Intervention NR
d. Height‐for‐age computed from height and age values · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted83 participantsVery low
Intervention NR
e. Weight‐for‐height computed from weight and height values · all populations, including pregnant women, from any country
Iodine fortification of foods and condiments, other than salt, for preventing iodine deficiency disorders (2019) · Cochrane
no estimate extracted83 participantsVery low
Interventions targeting vehicular sources vs practice
All‐cause mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRLow
Interventions targeting industrial sources vs practice
Respiratory mortality · General population, as well as age‐specific subgroups (< 1 year; < 14 years; > 65 years)
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting industrial sources vs practice
Particulate matter (PM10) · General population, as well as age‐specific subgroups (< 1 year; < 14 years; > 65 years)
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting industrial sources vs practice
Fine particulate matter (PM2.5) · General population, as well as age‐specific subgroups (< 1 year; < 14 years; > 65 years)
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRLow
Interventions targeting industrial sources vs practice
Coarse particulate matter · General population, as well as age‐specific subgroups (< 1 year; < 14 years; > 65 years)
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting industrial sources vs practice
Combustion‐related particulate matter · General population, as well as age‐specific subgroups (< 1 year; < 14 years; > 65 years)
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting residential sources vs practice
All‐cause mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting residential sources vs practice
Cardiovascular mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRLow
Interventions targeting residential sources vs practice
Respiratory mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting residential sources vs practice
Particulate matter (PM10) · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting residential sources vs practice
Fine particulate matter (PM2.5) · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting vehicular sources vs practice
Cardiovascular mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRLow
Interventions targeting residential sources vs practice
Coarse particulate matter · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting residential sources vs practice
Combustion‐related particulate matter · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting multiple sources vs practice
All‐cause mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting multiple sources vs practice
Cardiovascular mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting multiple sources vs practice
Respiratory mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting multiple sources vs practice
Particulate matter (PM10) · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting multiple sources vs practice
Fine particulate matter (PM2.5) · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting multiple sources vs practice
Coarse particulate matter · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting multiple sources vs practice
Combustion‐related particulate matter · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRNo studies
Interventions targeting vehicular sources vs practice
Respiratory mortality · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRLow
Interventions targeting vehicular sources vs practice
Particulate matter (PM10) · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRVery low
Interventions targeting vehicular sources vs practice
Fine particulate matter (PM2.5) · General population
Interventions to reduce ambient particulate matter air pollution and their effect on health (2019) · Cochrane
no estimate extractedNRLow