evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

766 questions · 806 findings · 76 reviews · ENT

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 293 · 36.4%GRADE not reported 6 · 0.7%Very low 244 · 30.3%Low 170 · 21.1%Moderate 85 · 10.5%High 8 · 1%

Antihistamines vs placebo

Adverse effects: 1. Sedation · patients with motion sickness

Antihistamines may leads to higher adverse effects: sedation Assessed by: adverse effect questionnaire… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: impaired cognition Assessed by: adverse effect questionnaire (presence or absence given numerical values) · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: impaired cognition Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: blurred vision Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs scopolamine

Proportion of susceptible participants who did not experience any motion sickness symptoms under natural conditions Assessed by: self‐reported questionnaires6,7 · patients with motion sickness

It is very uncertain whether antihistamines changes proportion of susceptible participants who did not experience any… compared with scopolamine (very low certainty).

1 finding from 1 review

Ginkgo biloba vs placebo

Other adverse effects (gastrointestinal upset, headache, allergic reaction) · adults with tinnitus

Ginkgo biloba showed no clear difference in other adverse effects (gastrointestinal upset, headache, allergic… compared with placebo (low certainty).

1 finding from 1 review

Systemic corticosteroids plus intranasal steroid/mucolytic/decongestant vs no intervention

Psychophysical testing for recovery of sense of smell · adults with olfactory dysfunction for ≥ 4 weeks following COVID‐19 infection

It is very uncertain whether systemic corticosteroids plus intranasal… changes psychophysical testing for recovery of sense of smell compared with no intervention (very low certainty).

1 finding from 1 review