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Evidence found and GRADE certainty

380 questions · 393 findings · 51 reviews

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No studies found 96 · 24.4%GRADE not reported 45 · 11.5%Very low 64 · 16.3%Low 77 · 19.6%Moderate 63 · 16%High 48 · 12.2%

Decision aids for informed consent vs usual care

Participation in decision making: clinician‐controlled decision making ‐ all studies Assessed soon after consultation with clinician · adults considering treatment or screening decisions

Patient decision aids leads to lower participation in decision‐making: clinician‐controlled… compared with usual care (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental cancer detection in women with dense breasts: cohort studies · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography showed no clear difference in incremental cancer detection in women with dense breasts: RCT compared with mammography alone (high certainty).

2 findings from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental detection of invasive cancers · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography showed no clear difference in incremental detection of invasive cancers compared with mammography alone (low certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Interval cancer · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography showed no clear difference in interval cancer compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

False‐positive rate in women with dense breasts · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography leads to higher false‐positive rate in women with dense breasts compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

False‐negative rate in women with dense breasts · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography probably leads to lower false‐negative rate in women with dense breasts compared with mammography alone (moderate certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Biopsy rate in women with dense breasts · breast cancer screening in women at average risk with dense breasts

Mammography in combination with breast ultrasonography leads to higher biopsy rate in women with dense breasts compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Incremental cancer detection for women with non‐dense breasts: cohort studies · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography probably leads to higher incremental cancer detection for women with non‐dense breasts: RCT compared with mammography alone (moderate certainty).

2 findings from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Interval cancer · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography showed no clear difference in interval cancer compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

False‐positive rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography leads to higher false‐positive rate in women with non‐dense breasts compared with mammography alone (high certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

False‐negative rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography probably leads to lower false‐negative rate in women with non‐dense breasts compared with mammography alone (moderate certainty).

1 finding from 1 review

Mammography in combination with breast ultrasonography vs mammography alone

Biopsy rate in women with non‐dense breasts · breast cancer screening (non‐dense breasts)

Mammography in combination with breast ultrasonography leads to higher biopsy rate in women with non‐dense breasts compared with mammography alone (high certainty).

1 finding from 1 review