Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Cyanoacrylate vs alcohol

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in controlling the active variceal… compared with alcohol (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Failure of intervention Continuous variceal bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes failure of intervention Continuous variceal bleeding after… compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in control variceal bleeding compared with band ligation (very low certainty).

1 finding from 1 review

Restricted vs standard fluid management

Incidence of hypernatremia (serum sodium > 145 mEq/L) at end of intervention period (proportions) · late preterm and full‐term infants with transient tachypnea of the newborn

It is very uncertain whether restricted changes incidence of hypernatremia (serum sodium > 145 mEq/L) at end of… compared with standard fluid management (very low certainty).

1 finding from 1 review

Restricted vs standard fluid management

Incidence of hypoglycemia (blood glucose < 40 mg/dL) at end of intervention period (proportions) · late preterm and full‐term infants with transient tachypnea of the newborn

It is very uncertain whether restricted changes incidence of hypoglycemia (blood glucose < 40 mg/dL) at end of… compared with standard fluid management (very low certainty).

1 finding from 1 review

Restricted vs standard fluid management

Incidence of endotracheal ventilation (proportions) during hospital stay (for infants on no support or noninvasive support at the time of study entry) · late preterm and full‐term infants with transient tachypnea of the newborn

It is very uncertain whether restricted changes incidence of endotracheal ventilation (proportions) during hospital… compared with standard fluid management (very low certainty).

1 finding from 1 review

Restricted vs standard fluid management

Incidence of noninvasive (nasal CPAP or nasal ventilation) respiratory support during hospital stay · late preterm and full‐term infants with transient tachypnea of the newborn

It is very uncertain whether restricted changes incidence of noninvasive (nasal CPAP or nasal ventilation)… compared with standard fluid management (very low certainty).

1 finding from 1 review

Tricyclic antidepressants vs Other Drug for

Number not achieving 14 consecutive dry nights at the end of treatment ‐ amitriptyline vs placebo · children with nocturnal enuresis

It is very uncertain whether tricyclics changes number not achieving 14 consecutive dry nights at the end of… compared with another drug (very low certainty).

2 findings from 1 review

Tricyclic antidepressants vs behavioural interventions

Number not achieving 14 consecutive dry nights at the end of treatment ‐ amitriptyline vs placebo · children with nocturnal enuresis

It is very uncertain whether tricyclics changes number not achieving 14 consecutive dry nights at the end of… compared with behavioural interventions (very low certainty).

2 findings from 1 review

Tricyclic antidepressants vs behavioural interventions

Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs 3 step therapy (reassurance, retention control training + wakening, parental involvement) · children with nocturnal enuresis

Tricyclics may leads to higher number not achieving 14 consecutive dry nights at the end of… compared with behavioural interventions (low certainty).

1 finding from 1 review

Tricyclic antidepressants vs behavioural interventions

Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs 3 step therapy + motivation/counselling + education · children with nocturnal enuresis

Tricyclics may leads to higher number not achieving 14 consecutive dry nights at the end of… compared with behavioural interventions (low certainty).

1 finding from 1 review

Tricyclic antidepressants vs behavioural interventions

Number not achieving 14 consecutive dry nights or relapsing at · children with nocturnal enuresis

It is very uncertain whether tricyclics changes number not achieving 14 consecutive dry nights or relapsing at compared with behavioural interventions (very low certainty).

2 findings from 1 review