Findings

What do systematic reviews say?

1,281 questions · 1,307 findings · 212 reviews

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No studies found 256 · 19.6%GRADE not reported 125 · 9.6%Very low 266 · 20.4%Low 403 · 30.8%Moderate 208 · 15.9%High 49 · 3.7%

Medication or nutrition fall prevention interventions vs control: evidence from RCTs

Economic analysis · community‐dwelling older adults ≥ 65 years of age

The review found no eligible studies for this question.

1 finding from 1 review

Population‐based interventions for preventing falls and fall‐related injuries in older people 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic dopamine antagonist antiemetic medications vs placebo

Participants with ≥ 1 vomiting episode · adults receiving intravenous opioids

Prophylactic dopamine antagonist antiemetic medications showed no clear difference in vomiting (≥1 episode) compared with placebo (low certainty).

1 finding from 1 review

Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting 2022 · Cochrane Headline outcomes only
RR 1.18 [0.26, 5.32]
3 studies · 527 participants
Low

Prophylactic dopamine antagonist antiemetic medications vs placebo

Nausea · adults receiving intravenous opioids

Prophylactic dopamine antagonist antiemetic medications showed no clear difference in nausea (≥1 episode) compared with placebo (low certainty).

1 finding from 1 review

Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting 2022 · Cochrane Headline outcomes only
RR 0.55 [0.15, 2.03]
2 studies · 336 participants
Low

Prophylactic dopamine antagonist antiemetic medications vs placebo

Adverse events · adults receiving intravenous opioids

Prophylactic dopamine antagonist antiemetic medications showed no clear difference in adverse events compared with placebo (low certainty).

1 finding from 1 review

Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting 2022 · Cochrane Headline outcomes only
RR 2.34 [0.47, 11.61]
3 studies · 527 participants
Low

Prophylactic dopamine antagonist antiemetic medications vs placebo

Number of vomiting episodes · adults receiving intravenous opioids

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic dopamine antagonist antiemetic medications vs placebo

Nausea severity · adults receiving intravenous opioids

1 finding from 1 review

Prophylactic antiemetics for adults receiving intravenous opioids in the acute care setting 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 191 participants
Low

Medication management vs usual care

Adherence to iron chelation therapy (%, SD)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medication management vs usual care

SAEs

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medication management vs usual care

All‐cause mortality

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medication management vs usual care

Sustained adherence

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Medication management vs usual care

QoL

1 finding from 1 review

Interventions for improving adherence to iron chelation therapy in people with sickle cell disease or thalassaemia 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 48 participants
Very low

Pre‐emptive medication for cytomegalovirus (CMV) viraemia vs placebo/no treatment

All symptomatic CMV disease · solid organ transplant recipients with CMV viraemia

1 finding from 1 review

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 288 participants
Low

Pre‐emptive medication for cytomegalovirus (CMV) viraemia vs placebo/no treatment

CMV organ involvement · solid organ transplant recipients with CMV viraemia

1 finding from 1 review

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 217 participants
Low

Pre‐emptive medication for cytomegalovirus (CMV) viraemia vs placebo/no treatment

Acute rejection · solid organ transplant recipients with CMV viraemia

1 finding from 1 review

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 185 participants
Low

Pre‐emptive medication for cytomegalovirus (CMV) viraemia vs placebo/no treatment

All‐cause mortality · solid organ transplant recipients with CMV viraemia

1 finding from 1 review

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 176 participants
Low

Pre‐emptive medication for cytomegalovirus (CMV) viraemia vs placebo/no treatment

Graft loss · solid organ transplant recipients with CMV viraemia

1 finding from 1 review

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Very low

Pre‐emptive medication for cytomegalovirus (CMV) viraemia vs placebo/no treatment

Leucopenia · solid organ transplant recipients with CMV viraemia

1 finding from 1 review

Pre‐emptive treatment for cytomegalovirus viraemia to prevent cytomegalovirus disease in solid organ transplant… 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 114 participants
Low

Single‐component medication monitoring and adjustment intervention vs control

Prevalence of delirium · people at risk of delirium in institutional long‐term care

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing delirium in older people in institutional long‐term care 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Single‐component medication monitoring and adjustment intervention vs control

Incidence of delirium · people at risk of delirium in institutional long‐term care

Single‐component medication monitoring and adjustment intervention probably leads to lower incidence of delirium NH‐CAM compared with control (moderate certainty).

1 finding from 1 review

Interventions for preventing delirium in older people in institutional long‐term care 2019 · Cochrane Headline outcomes only
HR 0.42 [0.34, 0.51]
1 study · 7311 participants
Moderate

Single‐component medication monitoring and adjustment intervention vs control

Severity of delirium · people at risk of delirium in institutional long‐term care

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing delirium in older people in institutional long‐term care 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found