Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,539 questions · 2,602 findings · 424 reviews · Headline outcomes only

No studies found 572 · 22%GRADE not reported 189 · 7.3%Very low 527 · 20.3%Low 685 · 26.3%Moderate 514 · 19.8%High 115 · 4.4%

Longer self‐certification vs shorter self‐certification

CBA: Average duration of sickness absence periods in days · workers
2 findings from 1 review

Longer self‐certification vs shorter self‐certification

CBA: Number of sickness absence periods per worker · workers
2 findings from 1 review

Longer self‐certification vs shorter self‐certification

CBA: Average lost work time per 100 person‐years · workers
2 findings from 1 review

Oral aciclovir (long‐term) vs placebo

Incidence of herpes labialis during use of the preventative intervention · participants with recurrent herpes labialis
2 findings from 1 review

Oral long‐chain omega‐3 PUFAs vs oral omega‐6 PUFAs

Change in dry eye symptoms, measured using the OSDI score (ranging from 0 to 100 units, with a reduction in score indicating clinical improvement) at 1‐month (with actual · people with dry eyea

Oral long‐chain omega‐3 PUFAs showed no clear difference in change in dry eye symptoms, measured using the OSDI score (ranging… compared with oral omega‐6 PUFAs (moderate certainty).

1 finding from 1 review

Oral long‐chain omega‐3 PUFAs vs oral omega‐6 PUFAs

Change in tear osmolarity (measured in mOsmol/L, with reductions in osmolarity indicating clinical improvement) at 1‐month (with actual · people with dry eyea

Oral long‐chain omega‐3 PUFAs showed no clear difference in change in tear osmolarity (measured in mOsmol/L, with reductions in… compared with oral omega‐6 PUFAs (low certainty).

1 finding from 1 review

Adults: higher dose/longer course vs lower dose/shorter course

Exacerbations · Adults with acute asthma

It is very uncertain whether adults: higher dose/longer course changes new exacerbation in compared with lower dose/shorter course (very low certainty).

2 findings from 1 review