Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

241 questions · 259 findings · 26 reviews · Headline outcomes only

No studies found 52 · 20.1%GRADE not reported 20 · 7.7%Very low 76 · 29.3%Low 73 · 28.2%Moderate 27 · 10.4%High 11 · 4.2%

Omega‐3 vs omega‐6

Global impression of deterioration (investigator defined global impression of deterioration) · people with multiple sclerosis

Omega‐3 showed no clear difference in global impression of deterioration (investigator defined global… compared with omega‐6 (moderate certainty).

1 finding from 1 review

Intervention diet vs control diet

Remission · Patients with active Crohn's disease

It is very uncertain whether intervention diet changes induction of remission at 4 weeks ‐ High‐fiber, low refined… compared with control diet (very low certainty).

4 findings from 1 review
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Intervention diet vs control diet

Clinical relapse · Participants with Crohn's disease in remission

Intervention diet showed no clear difference in clinical relapse at 6 to 24 months ‐ Symptoms‐guided diet compared with control diet (low certainty).

4 findings from 1 review
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Intervention diet vs control diet

Clinical relapse · Patients with quiescent ulcerative colitis

It is very uncertain whether intervention diet changes clinical relapse at 6 months ‐ Anti‐inflammatory diet (Alberta‐based) compared with control diet (very low certainty).

3 findings from 1 review

Intervention diet vs control diet

Induction of remission (timeframe not reported) ‐ Symptoms‐guided diet · Patients with active Crohn's disease

It is very uncertain whether intervention diet changes induction of remission (timeframe not reported) ‐ Symptoms‐guided diet compared with control diet (very low certainty).

1 finding from 1 review