Immediate bond strength (MPa) · Glass-ionomer cement bonded to caries-affected dentin (in vitro)
SDF pretreatment with a rinsing step does not affect glass-ionomer cement bond strength to caries-affected dentin (MD -0.36 MPa, 95% CI -1.07 to 0.35; ungraded).
1 finding from 1 review
Immediate bond strength (MPa) · Glass-ionomer cement bonded to dentin (in vitro), sound or caries-affected
Prior SDF application does not influence the immediate bond strength of glass-ionomer cement to dentin (MD -0.11 MPa, 95% CI -0.54 to 0.31; ungraded).
1 finding from 1 review
Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth
A second meta-analysis reported odds ratios of 2.44 to 3.63 favouring 38% SDF over fluoride varnish/water for caries arrest (ungraded).
2 findings from 1 review
OR (caries arrest) OR 2.44-3.63 (range); 2.44 = Chu estimate including 30% SDF
3 studies
GRADE not reported
Proportion (caries arrest) 81 [68, 89]
12 studies
GRADE not reported
Immediate bond strength (MPa) · Dental adhesives bonded to caries-affected dentin (in vitro)
Prior SDF followed by a rinsing step significantly increases adhesive bond strength to caries-affected dentin (MD -4.79 MPa favoring SDF, 95% CI -9.19 to -0.40; ungraded).
1 finding from 1 review
Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth
Twice-yearly 38% SDF was reported to arrest more caries than once-yearly application (24-month rates 91% vs 79%; ungraded).
1 finding from 1 review
Immediate bond strength (MPa) · Dental adhesives bonded to caries-affected dentin (in vitro)
Only one study assessed SDF without a rinsing step on adhesive bonding to caries-affected dentin (Kucukyilmaz 2016, which reported impaired bond strength); no meta-analysis was possible, so no pooled estimate is available.
1 finding from 1 review
total microbial load (log10 CFU) · humans with open primary dentine caries
In one study, hardness category differences exceeded color category differences; no meta-analysis was conducted.
1 finding from 1 review
Treatment success rate · Primary teeth with dentin caries lesions on occlusal surfaces
CRT with compomer ranked first for treatment success in the occlusal-surface network (low certainty).
1 finding from 1 review
Treatment success rate · Primary teeth with dentin caries lesions on occlusoproximal surfaces
The Hall technique ranked first for treatment success in the occlusoproximal-surface network (low certainty).
1 finding from 1 review
Treatment failure (annual failure rate) · Children (aged 3-8 years) with 2-surface occluso-proximal dentine caries in primary molars, no pulp therapy
Preformed metal (Hall) crowns had a low reported annual failure rate (3.1%) versus compomer (14.7%) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review
Mineral loss (transversal microradiography) · Enamel/dentin specimens with initial caries lesions (or sound surfaces) in intraoral (in situ) appliances worn by patients
Under remineralizing conditions, nHA produced significantly more remineralization than the negative control (MD 350, 95% CI 179 to 521; very low certainty).
2 findings from 1 review
Restoration failure · Children (3-13 years) with dentine caries in primary teeth, no pulpal involvement
ART with GIC was reported to increase the odds of restoration failure versus conventional restoration (OR 1.60; ungraded).
1 finding from 1 review
Discomfort during treatment · Children (3-10 years) with dentine caries in primary molars
The reported estimate for treatment discomfort with the Hall Technique versus conventional restorations was inconclusive (ungraded).
1 finding from 1 review
RR 1.67 [0.65, 4.25]
2 studies
GRADE not reported
Mineral loss (transversal microradiography) · Enamel/dentin specimens with initial caries lesions (or sound surfaces) in intraoral (in situ) appliances worn by patients
Under demineralizing conditions, nHA allowed significantly more enamel demineralization than NaF (MD 1625, 95% CI 553 to 2697; very low certainty).
2 findings from 1 review
Pain during the procedure (primary analysis) · Children (3-13 years) with dentine caries in primary teeth, no pulpal involvement
The reported estimate for procedural pain with ART versus conventional treatment was inconclusive (ungraded).
1 finding from 1 review
Patient discomfort during treatment (anxiety scale) · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
One study found no significant difference in patient discomfort between SDF and ART (p = 0.15; ungraded).
1 finding from 1 review
Adverse events: gingival bleeding · Children (3-10 years) with dentine caries in primary molars
The reported estimate for gingival bleeding with preformed metal crowns was inconclusive (ungraded).
1 finding from 1 review
RR 1.09 [0.42, 2.86]
2 studies
GRADE not reported
Intervention not reported
Mean number of arrested caries surfaces
1 finding from 1 review
Restoration failure · Children (3-10 years) with dentine caries in primary molars
The Hall Technique was reported to reduce restoration and major failure versus conventional restorations (3% vs 37%; ungraded).
1 finding from 1 review
3% (HT) vs 37% (control)
1 study
GRADE not reported
Treatment failure (annual failure rate) · Children with moderately deep dentine caries in primary molars, no pulp therapy
Etch-and-rinse adhesion failed more than self-etch (19.5% vs 7.0% annual failure) in one RCT; low quality of evidence (ungraded).
1 finding from 1 review