Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

236 questions · 244 findings · 40 reviews · Acute Respiratory Infections

No studies found 16 · 6.6%GRADE not reported 32 · 13.1%Very low 32 · 13.1%Low 60 · 24.6%Moderate 82 · 33.6%High 22 · 9%

Carbapenems vs non‐carbapenems

Clinical cure · Ventilator‐associated pneumonia

Carbapenems probably leads to higher clinical cure (ITT) compared with non‐carbapenems (moderate certainty).

2 findings from 1 review

Written information for patients (or parents of child patients) vs usual care

Reconsultations · patients (or parents of child patients) with acute upper respiratory tract infections

Written information for patients (or parents of child patients) showed no clear difference in reconsultation rates compared with usual care (moderate certainty).

1 finding from 1 review

Written information for patients (or parents of child patients) vs usual care

Patient satisfaction with consultation · patients (or parents of child patients) with acute upper respiratory tract infections

Written information for patients (or parents of child patients) showed no clear difference in patient satisfaction with consultation compared with usual care (moderate certainty).

1 finding from 1 review

Intervention not reported

Clinical cure rates at day 8 ± 1 · adults with acute laryngitis

It is very uncertain whether the intervention changes clinical cure rates at day 8 ± 1 (very low certainty).

1 finding from 1 review

Intervention not reported

Clinical cure rates at day 8 ± 1 · adults with acute laryngitis

It is very uncertain whether the intervention changes clinical cure rates at day 8 ± 1 (very low certainty).

1 finding from 1 review

Intervention not reported

Laryngitis at 1 week · adults with acute laryngitis

The intervention showed no clear difference in laryngitis at 1 week (low certainty).

1 finding from 1 review

Intervention not reported

Laryngitis at 2 weeks · adults with acute laryngitis

The intervention showed no clear difference in laryngitis at 2 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Patients having voice disturbance at 1 week · adults with acute laryngitis

The intervention showed no clear difference in patients having voice disturbance at 1 week (low certainty).

1 finding from 1 review

Intervention not reported

Patients having voice disturbance at 2 weeks · adults with acute laryngitis

The intervention showed no clear difference in patients having voice disturbance at 2 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Meningitis‐related mortality · patients with a recent BSF independent of the presence or severity of CSF leakage

The intervention showed no clear difference in meningitis‐related mortality (moderate certainty).

1 finding from 1 review

Intervention not reported

Incidence of pulmonary tuberculosis in children with HIV infection ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under

The intervention showed no clear difference in incidence of pulmonary tuberculosis in children with HIV infection ‐… (moderate certainty).

1 finding from 1 review