Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

633 questions · 668 findings · 122 reviews · Headline outcomes only

No studies found 144 · 21.6%GRADE not reported 27 · 4%Very low 154 · 23.1%Low 194 · 29%Moderate 119 · 17.8%High 30 · 4.5%

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Prolapse on examination ‐ Posterior compartment prolapse · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in prolapse on examination ‐ Posterior compartment prolapse compared with alternative vaginal native tissue apical suspension (moderate certainty).

1 finding from 1 review

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Bladder function ‐ Stress incontinence · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in bladder function ‐ Stress urinary incontinence compared with alternative vaginal native tissue apical suspension (low certainty).

1 finding from 1 review

Sacral colpopexy: laparoscopic vs alternative approach

Prolapse on examination (Stage 2 or above) ‐ Any recurrent prolapse · women with apical vaginal prolapse

Sacral colpopexy: laparoscopic showed no clear difference in prolapse on examination (Stage 2 or more): Any recurrent prolapse compared with alternative approach (low certainty).

1 finding from 1 review

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID

It is very uncertain whether regimens containing macrolides (azithromycin) changes clinical cure according to criteria established by study authors… compared with regimens containing tetracycline (doxycycline) (very low certainty).

2 findings from 1 review

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Clinical cure according to criteria established by study authors Severe PID · women with PID

Regimens containing macrolides (azithromycin) showed no clear difference in clinical cure according to criteria established by study authors… compared with regimens containing tetracycline (doxycycline) (low certainty).

1 finding from 1 review

Regimens containing macrolides (azithromycin) vs regimens containing tetracycline (doxycycline)

Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID

Regimens containing macrolides (azithromycin) showed no clear difference in adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing tetracycline (doxycycline) (low certainty).

1 finding from 1 review