Findings

What do systematic reviews say?

747 questions · 815 findings · 144 reviews

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No studies found 154 · 18.9%GRADE not reported 147 · 18%Very low 164 · 20.1%Low 199 · 24.4%Moderate 121 · 14.8%High 30 · 3.7%

Tacrolimus 0.1% cream vs placebo

Adverse events of medication, leading to discontinuation or significant morbidity · people with discoid lupus erythematosus

1 finding from 1 review

Drugs for discoid lupus erythematosus 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Moderate

Summary of findings: acrylic vs silicone punctal plugs

Symptomatic improvement · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Ocular surface staining · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Aqueous tear production · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Tear film stability · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Artificial tear use · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings: acrylic vs silicone punctal plugs

Adverse events · mostly women with dry eye syndrome

1 finding from 1 review

Punctal occlusion for dry eye syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Awareness of prolapse · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in awareness of prolapse compared with alternative vaginal native tissue apical suspension (moderate certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 0.88 [0.68, 1.15]
1 study · 267 participants
Moderate

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Surgery for recurrent prolapse · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in surgery for recurrent prolapse compared with alternative vaginal native tissue apical suspension (moderate certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 1.86 [0.66, 5.28]
1 study · 228 participants
Moderate

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Prolapse on examination ‐ Anterior compartment prolapse · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in prolapse on examination ‐ Anterior compartment prolapse compared with alternative vaginal native tissue apical suspension (moderate certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 1.14 [0.88, 1.48]
3 studies · 588 participants
Moderate

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Prolapse on examination ‐ Apical compartment prolapse · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in prolapse on examination ‐ Apical compartment prolapse compared with alternative vaginal native tissue apical suspension (moderate certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 0.8 [0.38, 1.67]
3 studies · 587 participants
Moderate

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Prolapse on examination ‐ Posterior compartment prolapse · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in prolapse on examination ‐ Posterior compartment prolapse compared with alternative vaginal native tissue apical suspension (moderate certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 1.36 [0.79, 2.32]
3 studies · 588 participants
Moderate

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Bladder function ‐ Stress incontinence · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in bladder function ‐ Stress urinary incontinence compared with alternative vaginal native tissue apical suspension (low certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 1.6 [0.64, 3.98]
1 study · 228 participants
Low

Vaginal uterosacral colpopexy vs alternative vaginal native tissue apical suspension

Painful intercourse ‐ Dyspareunia · women with apical vaginal prolapse

Vaginal uterosacral colpopexy showed no clear difference in painful intercourse ‐ Dyspareunia compared with alternative vaginal native tissue apical suspension (low certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 1.19 [0.73, 1.95]
1 study · 228 participants
Low

Sacral colpopexy: laparoscopic vs alternative approach

Awareness of prolapse: Laparoscopic versus open · women with apical vaginal prolapse

Sacral colpopexy: laparoscopic showed no clear difference in awareness of prolapse: Laparoscopic versus open compared with alternative approach (low certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 2.06 [0.4, 10.54]
2 studies · 193 participants
Low

Sacral colpopexy: laparoscopic vs alternative approach

Surgery for recurrent prolapse · women with apical vaginal prolapse

Sacral colpopexy: laparoscopic showed no clear difference in surgery for recurrent prolapse compared with alternative approach (moderate certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 0.77 [0.26, 2.31]
3 studies · 208 participants
Moderate

Sacral colpopexy: laparoscopic vs alternative approach

Prolapse on examination (Stage 2 or above) ‐ Any recurrent prolapse · women with apical vaginal prolapse

Sacral colpopexy: laparoscopic showed no clear difference in prolapse on examination (Stage 2 or more): Any recurrent prolapse compared with alternative approach (low certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 1.29 [0.64, 2.56]
3 studies · 225 participants
Low

Sacral colpopexy: laparoscopic vs alternative approach

Any complications (Clavien‐Dindo > 3) · women with apical vaginal prolapse

It is very uncertain whether sacral colpopexy: laparoscopic changes any complications (Clavien‐Dindo > 3) compared with alternative approach (very low certainty).

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
RR 1.26 [0.17, 9.44]
2 studies · 193 participants
Very low

Sacral colpopexy: laparoscopic vs alternative approach

Operating time · women with apical vaginal prolapse

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 241 participants
Very low

Sacral colpopexy: laparoscopic vs alternative approach

Length of hospital stay · women with apical vaginal prolapse

1 finding from 1 review

Surgery for women with apical vaginal prolapse 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 246 participants
Low