Findings

What do systematic reviews say?

9 questions · 9 findings · 2 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 33.3%Low 5 · 55.6%Moderate 1 · 11.1%High 0 · 0%

Benzodiazepines vs placebo

Leaving the study early · adults with panic disorder

Benzodiazepines may leads to lower total number of dropouts compared with placebo (low certainty).

1 finding from 1 review

Benzodiazepines versus placebo for panic disorder in adults 2019 · Cochrane Headline outcomes only
RR 0.5 [0.39, 0.64]
21 studies · 3558 participants
Low

Selective serotonin reuptake inhibitors vs benzodiazepines

Leaving the study early · adults with panic disorder

It is very uncertain whether SSRIs changes total number of dropouts compared with benzodiazepines (very low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.71 [1.03, 2.84]
1 study · 154 participants
Very low

Antidepressants vs benzodiazepines

Leaving the study early · adults with panic disorder

It is very uncertain whether antidepressants changes total number of dropouts compared with benzodiazepines (very low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.64 [1.03, 2.63]
7 studies · 1449 participants
Very low

Tricyclic antidepressants vs benzodiazepines

Leaving the study early · adults with panic disorder

It is very uncertain whether TCAs changes total number of dropouts compared with benzodiazepines (very low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.67 [0.93, 2.99]
6 studies · 1295 participants
Very low

Tricyclic antidepressants vs SSRI

Leaving the study early · adults with panic disorder

TCAs showed no clear difference in total number of dropouts compared with SSRI (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 0.98 [0.65, 1.48]
7 studies · 928 participants
Low

Tricyclic antidepressants vs MAOI

Leaving the study early · adults with panic disorder

TCA showed no clear difference in total number of dropouts compared with MAOI (moderate certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 0.84 [0.61, 1.17]
2 studies · 228 participants
Moderate

Selective serotonin reuptake inhibitors vs MAOI

Leaving the study early · adults with panic disorder

SSRIs showed no clear difference in total number of dropouts compared with MAOIs (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1 [0.07, 14.55]
1 study · 30 participants
Low

Selective serotonin reuptake inhibitors vs SNRIs

Leaving the study early · adults with panic disorder

SSRIs showed no clear difference in total number of dropouts compared with SNRIs (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.11 [0.74, 1.65]
2 studies · 991 participants
Low

Selective serotonin reuptake inhibitors vs NaSSAs

Leaving the study early · adults with panic disorder

SSRIs showed no clear difference in total number of dropouts compared with naSSAs (low certainty).

1 finding from 1 review

Antidepressants and benzodiazepines for panic disorder in adults 2016 · Cochrane Headline outcomes only
RR 1.5 [0.29, 7.73]
1 study · 30 participants
Low