Findings

What do systematic reviews say?

5 questions · 10 findings · 2 reviews · Colorectal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 40%Low 0 · 0%Moderate 6 · 60%High 0 · 0%

Laparoscopic vs open appendectomy

Wound infection · patients with suspected appendicitis

Subgroup analysis (publication date) ‐ Laparoscopic probably leads to lower wound infections compared with open appendectomy (moderate certainty).

3 findings from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.37 [0.27, 0.51]
19 studies · 2217 participants
Moderate
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.42 [0.35, 0.51]
63 studies · 7612 participants
Moderate
Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.27 [0.14, 0.52]
5 studies · 783 participants
Moderate

Laparoscopic vs open appendectomy

Surgical complications ‐ wound infection · patients with suspected appendicitis

Laparoscopic probably leads to lower wound infections (rate) compared with open appendectomy (moderate certainty).

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.25 [0.15, 0.42]
10 studies · 1245 participants
Moderate

Antibiotic prophylaxis vs placebo

Wound infection · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) compared with placebo (very low certainty).

2 findings from 1 review

Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or… 2020 · Cochrane Headline outcomes only
RR 0.86 [0.56, 1.33]
5 studies · 1865 participants
Very low
Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or… 2020 · Cochrane Headline outcomes only
RR 0.61 [0.48, 0.78]
22 studies · 6443 participants
Moderate

Antibiotic prophylaxis vs placebo

All wound infections (SSSI + DSSI) ‐ low infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ low infection risk environment compared with placebo (very low certainty).

2 findings from 1 review

Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or… 2020 · Cochrane Headline outcomes only
RR 0.63 [0.28, 1.41]
4 studies · 1302 participants
Very low
Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or… 2020 · Cochrane Headline outcomes only
RR 0.71 [0.44, 1.14]
9 studies · 3100 participants
Moderate

Antibiotic prophylaxis vs placebo

All wound infections (SSSI + DSSI) ‐ high infection risk environment · prevention of postoperative wound infection in adults undergoing open elective inguinal or femoral hernioplasty hernia repair

It is very uncertain whether antibiotic prophylaxis changes all wound infections (SSSI + DSSI) ‐ high infection risk environment compared with placebo (very low certainty).

2 findings from 1 review

Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or… 2020 · Cochrane Headline outcomes only
RR 0.99 [0.58, 1.68]
1 study · 563 participants
Very low
Antibiotic prophylaxis for prevention of postoperative wound infection in adults undergoing open elective inguinal or… 2020 · Cochrane Headline outcomes only
RR 0.58 [0.43, 0.77]
13 studies · 3343 participants
Very low