Findings

What do systematic reviews say?

3 questions · 4 findings · 2 reviews · Colorectal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 0 · 0%High 3 · 75%

Antibiotics vs placebo or no antibiotic

Surgical complications ‐ wound infection · patients with colorectal surgery

Antibiotic leads to lower surgical wound infection (SWI) compared with no antibiotic/placebo (high certainty).

1 finding from 1 review

Antimicrobial prophylaxis for colorectal surgery 2014 · Cochrane Headline outcomes only
RR 0.34 [0.28, 0.41]
30 studies · 2455 participants
High

Mesh vs non‐mesh repair

Surgical complications ‐ wound infection · adults undergoing inguinal and femoral hernia repair

Mesh showed no clear difference in surgical complications ‐ wound infection compared with non‐mesh repair (low certainty).

1 finding from 1 review

Mesh versus non‐mesh for inguinal and femoral hernia repair 2018 · Cochrane Headline outcomes only
RR 1.29 [0.89, 1.86]
21 studies · 4540 participants
Low

Combined oral and intravenous vs oral or intravenous alone

Wound infection · colorectal surgery

Combined oral and intravenous leads to lower surgical wound infection: oral + iv versus iv alone compared with oral or intravenous alone (high certainty).

2 findings from 1 review

Antimicrobial prophylaxis for colorectal surgery 2014 · Cochrane Headline outcomes only
RR 0.55 [0.43, 0.71]
15 studies · 2929 participants
High
Antimicrobial prophylaxis for colorectal surgery 2014 · Cochrane Headline outcomes only
RR 0.52 [0.35, 0.76]
9 studies · 1880 participants
High